Month: <span>January 2023</span>

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Loyalty card data could help to identify ovarian cancer symptoms sooner
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Loyalty card data could help to identify ovarian cancer symptoms sooner

by Lancaster University The study of almost 300 women found that pain and indigestion medication purchases were higher in women who were subsequently diagnosed with ovarian cancer, compared to women who did not have ovarian cancer. Credit: Lancaster University Loyalty card data on over-the-counter medicine purchases could help spot ovarian cancer cases earlier according to...

SGLT2 inhibitor found to reduce endothelial dysfunction associated with ALDH2 alcohol face flushing variant
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SGLT2 inhibitor found to reduce endothelial dysfunction associated with ALDH2 alcohol face flushing variant

by Bob Yirka, Medical Xpress A model showing Alda-1 bound to ALDH2, with the catalytic tunnel of ALDH2 enlarged (B). Credit: H. Guo, et al., Science Translational Medicine (2023) A team of researchers at Stanford University working with two colleagues from Greenstone Biosciences has found that an SGLT2 inhibitor can reduce endothelial dysfunction commonly associated with the ALDH2 alcohol...

Wearable Sensor Uses Ultrasound to Provide Cardiac Imaging On the Go
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Wearable Sensor Uses Ultrasound to Provide Cardiac Imaging On the Go

UC San Diego engineers lead development of a powerful new ultrasound sensor system for cardiac imaging that even works during a workout The unique design of the sensor makes it ideal for bodies in motion. Photo David Baillot, Jacobs School of Engineering, UC San Diego. Published Date January 25, 2023 By: Emerson Dameron – [email protected] Ioana Patringenaru – [email protected]...

Computer Model of Influenza Virus Shows Universal Vaccine Promise
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Computer Model of Influenza Virus Shows Universal Vaccine Promise

By Michelle Franklin – [email protected] According to the World Health Organization, each year there are an estimated 1 billion cases of influenza, between 3-5 million severe cases and up to 650,000 influenza-related respiratory deaths globally. Seasonal flu vaccines must be reformulated each year to match the predominantly circulating strains. When the vaccine matches the predominant...

Drug that targets tauopathies in mice reveals sex differences in response
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Drug that targets tauopathies in mice reveals sex differences in response

by University of California, San Francisco Microglial cells. Credit: University of California, San Francisco (UCSF) Microglia are cells that are central to both brain health as well as disease progression in many neurological conditions. Normally, microglia stabilize the brain by clearing out damaged neurons and protein plaques often associated with dementia and other brain diseases. But...

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TEST MEASURES THOUSANDS OF MOLECULES FROM 1 BLOOD DROP

The new approach combines a microsampling device—a tool used to self-administer a finger prick—with “multi-omics” technologies, which simultaneously analyze a vast array of proteins, fats, by-products of metabolism, and inflammatory markers. “Even more importantly, we’ve shown you can collect the blood drop at home and mail it into the lab,” says Michael Snyder, director of...

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Scientists identify drug that could extend lifespan

UNIVERSITY OF AUCKLAND The age-old quest for immortality has taken a step forward with the results of an Aotearoa New Zealand study just published in leading international journal Nature Ageing. The Waipapa Taumata Rau, University of Auckland trial demonstrates that long-term treatment of healthy mice from middle-age (one year) with a drug currently used to treat...

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Corona vaccine based on new technology tested in clinical study

RADBOUD UNIVERSITY MEDICAL CENTER A new COVID-19 vaccine based on a different platform than current vaccines on the market has been tested in humans for the first time by researchers at Radboud university medical center. Administration of this vaccine in healthy study participants was well tolerated and led to a good immune response. The effectiveness of the...

Tiny ion is crucial for HIV replication, say chemists
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Tiny ion is crucial for HIV replication, say chemists

by Louise Lerner, University of Chicago A new study shows how a handful of ions are crucial to the process by which HIV replicates. On the left is a simulation of a normal capsule; on the right is a simulation of a capsule formed without the IP6 ions. Without the ions, the capsule cannot close...

Researcher takes another step toward discovering how a brain molecule could halt MS
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Researcher takes another step toward discovering how a brain molecule could halt MS

by Gillian Rutherford, University of Alberta Graphical abstract. Credit: Stem Cell Reports (2023). DOI: 10.1016/j.stemcr.2022.12.001 A University of Alberta researcher is one step closer to demonstrating the potential of a brain molecule called fractalkine to halt and even reverse the effects of multiple sclerosis and other neurodegenerative diseases. Multiple sclerosis is an autoimmune disease in which the...