by Wiley Credit: CC0 Public Domain New research published in the Journal of the American Geriatrics Society indicates that social isolation is common among older U.S. adults, and it increases their likelihood of developing dementia. Among 5,022 participants of the National Health and Aging Trends Study, a longitudinal and nationally representative study of older adults in the United States,...
by American Association for Cancer Research Credit: Unsplash/CC0 Public Domain Posoleucel, an investigational allogeneic off-the-shelf T-cell therapy that simultaneously targets six different viruses, demonstrated promising antiviral efficacy and safety in a phase II study of patients who had undergone stem cell transplantation to treat their cancer or other blood diseases, according to a publication in...
by Devorah Fischler, University of Pennsylvania Co-culture of organoids in OCTOPUS. Credit: Nature Methods (2022). DOI: 10.1038/s41592-022-01643-8 When it comes to human bodies, there is no such thing as typical. Variation is the rule. In recent years, the biological sciences have increased their focus on exploring the poignant lack of norms between individuals, and medical and pharmaceutical researchers are...
by Bob Yirka, Medical Xpress Random Walk with Restart-based Topological Gene Enrichment of Genome-wide Significant Varicose Veins Variants. a) Workflow of cell-type specific SNP-to-gene assignment and gene set enrichment analysis. Hi-C contact maps were generated from human umbilical vein endothelial cells (HUVECs) and human coronary artery smooth muscle cells (HCASMCs) and the intersecting H-MAGMA assigned...
by Bob Yirka, Medical Xpress The number of injected hfNPCs inversely correlates with brain volume loss. Color-coded areas of brain atrophy (blue) and growth (red) representing PBVC at 2 years from hfNPC transplantation in two representative patients, respectively, receiving a low dose (a, red in c) and high dose (b, green in c) of hfNPCs....
by NYU Langone Health Credit: Unsplash/CC0 Public Domain Severe inflammation weakens the body’s ability to kill cancerous blood cells in people with acute myeloid leukemia (AML), a new study shows. Experiments in human cells also revealed how increasing levels of inflammation, marked by an aggressive reaction of immune cells in the bone marrow, altered the makeup of immune B cells...
by Shana K. Hutchins, Texas A&M University Translating human GWAS signals to functional outcomes with variant-to-gene mapping. (A) Leveraging existing insomnia human GWAS loci, we identified proxy SNPs in strong linkage disequilibrium with sentinel SNPs using both genome-wide ATAC-seq and high-resolution promoter-focused Capture C data from iPSC-derived NPCs and then performed high-throughput sleep and activity...
January 9, 2023 – By Nina Bai In a Stanford Medicine-led study, patients whose sense of smell was affected by COVID-19 were helped by injections of platelet-rich plasma derived from their own blood.frantic00/Shutterstock.com Early in the pandemic, when people with COVID-19 began reporting that they lost their sense of smell, Zara Patel, MD, figured as much. A...
By MEIKE LEONARD FOR DAILYMAIL.COM PUBLISHED: 07:33 EST, 11 January 2023 | UPDATED: 07:41 EST, 11 January 2023 A simple online survey can diagnose autism with up to 95 percent accuracy, a study suggests. Researchers have developed a 39-item questionnaire to help parents navigate a notoriously tricky diagnosis process. It is the latest promising development in autism screening, coming just days...
By CEDARS-SINAI MEDICAL CENTER JANUARY 10, 2023 Postural Orthostatic Tachycardia Syndrome (POTS) is a disorder that affects the autonomic nervous system and is characterized by an abnormal increase in heart rate upon standing up. This can cause symptoms such as lightheadedness, fainting, fatigue, and headaches. Smidt Heart Institute researchers show the risk of developing postural orthostatic tachycardia syndrome, or...
