by Georgia Institute of Technology Model. Credit: Georgia Tech Cats always land on their feet, but what makes them so agile? Their unique sense of balance has more in common with humans than it may appear. Researchers at the Georgia Institute of Technology are studying cat locomotion to better understand how the spinal cord works to help...
by Mass General Brigham Age-related matrix stiffening in articular cartilage initiates pathogenic mechanotransductive signaling, driving chondrocyte dysfunction as well as disrupted cartilage integrity through Klotho promoter hypermethylation. Portions of the figure were created with biorender.com. Credit: Ambrosio et al, Nature Communications Researchers in the United States and Japan have discovered a new mechanism that links age-related cartilage tissue...
by Brigham and Women’s Hospital Phenotypic profile of patient-derived HIV-1-infected cells circulating in PB. a, Global visualization of phenotypic properties of HIV-1-infected CD4+ T cells from five study participants using two-dimensional UMAP plots; five computationally defined spherical clusters reflecting phenotypically distinct mCD4+ T cell subsets are shown. One plot is shown for each cell category. b, A...
9 January 2023 Representative images of a WM983B melanoma cell nucleus with a nuclear envelope bleb stained for Lamin A/C (green), Lamin B1 (magenta) and DNA (blue). Scale bar, 10 μm The study, published today in Nature Cell Biology, modelled the behaviour of aggressive melanoma cells that are able to change the shape of their nucleus to...
2022 was a banner year for artificial intelligence, and particularly taking into account the launch of OpenAI’s incredibly impressive ChatGPT, the industry is showing no sign of stopping. But for some industry leaders, chatbots and image-generators are far from the final robotic frontier. Next up? Consciousness. “This topic was taboo,” Hod Lipson, the mechanical engineer in charge of the...
By Rich Haridy January 08, 2023 Researchers are attempting to understand the risk factors that make different people more susceptible to various long COVID symptoms Depositphotos Using machine learning to track symptom clusters in around 35,000 COVID patients, researchers have identified four distinct types of long COVID. The findings suggest long COVID is a diverse disease with...
The discovery will improve diagnosis and open new treatment avenues for this progressive condition. Late-onset cerebellar ataxias (LOCA) are a heterogenous group of neurodegenerative diseases that manifest in adulthood with unsteadiness. One to three in 100,000 people worldwide will develop a late-onset ataxia. Until recently, most patients with late-onset ataxia had remained without a genetic...
UNIVERSITY OF EASTERN FINLAND Fewer cases of melanoma were observed among regular users of vitamin D supplements than among non-users, a new study finds. People taking vitamin D supplements regularly also had a considerably lower risk of skin cancer, according to estimates by experienced dermatologists. The study, conducted in collaboration between the University of Eastern...
MEDICAL UNIVERSITY OF VIENNA A MedUni Vienna research team has discovered a highly potent biomarker for clinical response to CAR-T cell therapy, describing the prerequisites for optimal use of this novel therapy for lymphoma treatment. The current findings are an essential step forward towards optimizing this promising therapy. The results of the study were recently published in the...
KTH, ROYAL INSTITUTE OF TECHNOLOGY IMAGE: THE YELLOW BAR IN THIS READOUT OF PROTEIN GFAP INDICATES ELEVATED EXPRESSION IN THE BLOOD OF PATIENTS WITH BRAIN TUMORS. (IMAGE: HUMAN DISEASE BLOOD ATLAS) CREDIT: HUMAN DISEASE BLOOD ATLAS Cancer prediction medicine gained a boost with the recent unveiling of a new cancer protein profile database compiled from...
