by London Medical Laboratory Credit: Pixabay/CC0 Public Domain Levels of LDL cholesterol, the so-called “bad cholesterol” that blocks arteries, have been found to be 20% higher immediately after Christmas compared to the summer. A leading testing expert is warning this could lead to increased risk of heart attacks or strokes. He’s urging everyone to check out their...
Monkeypox viruses remain sensitive to the available drugs
by Goethe University Frankfurt am Main Infection of primary human cells with mpox virus (MPXV) isolates obtained from patients during the current outbreak and sensitivity to antiviral drugs. Credit: New England Journal of Medicine (2022). DOI: 10.1056/NEJMc2212136 The mpox virus is closely related to the smallpox virus (variola virus), which caused large, deadly outbreaks before it was...
MIS-C has been more common and more severe than previously reported, study finds
By Deidre McPhillips, CNNPublished 11:00 AM EST, Thu January 5, 2023 Although still rare, MIS-C after Covid-19 has been more common and more severe than previously reported, and there are significant racial disparities in cases, according to a study published Thursday in JAMA Network Open. Multisystem inflammatory syndrome in children – which primarily emerges after a Covid-19...
Acute Care in the Home Gets Waiver Extension
Larry Beresford January 04, 2023 The hospital at home model of providing acute-level healthcare in the residences of patients who are sick enough to meet hospital admission standards continues to generate interest from hospitals, payers, and policymakers. But uncertain regulatory footing, lack of coverage by many private insurers, reluctance by some physicians to refer, and low patient...
Study compares effectiveness of Pfizer vs. Moderna booster COVID vaccines after third dose
By Neha Mathur Jan 3 2023 Reviewed by Emily Henderson, B.Sc. In a recent scientific paper published in the journal Nature Microbiology, researchers reproduced two target trials using electronic health records (EHRs) of the Department of Veterans Affairs (VA) to compare the effectiveness of the third dose of BNT162b2 or messenger ribonucleic acid (mRNA)-1273 vaccine among...
Formation of pores in mitochondrial membrane elucidated
UNIVERSITY OF FREIBURG IMAGE: MODEL OF THE BETA-BARREL PROTEIN PORIN FROM BAKER’S YEAST FOUND IN THE MITOCHONDRIAL OUTER MEMBRANE. CREDIT: ILLUSTRATION: CHRISTOPHE WIRTH/UNIVERSITY OF FREIBURG Mitochondria are considered to be the power plants of cells and are essential for human metabolism. Dysfunction in 40 percent of mitochondrial proteins are associated with human diseases, which is...
Study illuminates sugar’s role in common kidney disease
by University of Washington School of Medicine An illustration shows fluid absorption and cyst expansion in kidney organoids infected with polycystic kidney disease (PKD). The outward-facing proximal tubular epithelial cells (green) absorb fluid, generating pressure that causes expansion and stretching of the epithelium, creating cysts. It is unclear why normal epithelial cells resist cyst formation....
Medical providers often lack training in caring for those with disabilities
by CU Anschutz Medical Campus Credit: Pixabay/CC0 Public Domain Patients with disabilities often face medical providers who make inaccurate assumptions about their quality of life that can lead to paternalism and substandard care, according to an essay published this week in the New England Journal of Medicine (NEJM). “The term ‘ableism’ is not as well-known as the term ‘racism’ but it...
Fungi that cause serious lung infections are now found throughout the US
by Tina Hesman Saey, Washington University School of Medicine in St. Louis Credit: Washington University School of Medicine in St. Louis Three types of fungi that cause serious lung infections and were once thought to be confined to certain regions of the United States are now widespread. In 1955, Histoplasma fungi grew mainly in Midwest soil and...
COVID drug Paxlovid was hailed as a game-changer. What happened?
Max Kozlov Tablets of Paxlovid, which reduces risk of severe COVID-19, are inspected by a laboratory technician.Credit: Thomas Hansmann/AP/Shutterstock When clinical trial data for the antiviral drug Paxlovid emerged in late 2021, physicians hailed its astonishing efficacy — a reduction of nearly 90% in the risk of severe COVID-19. But more than a year later, COVID-19 remains...