JANUARY 5TH, 2023 CONN HASTINGS DIAGNOSTICS, ENT, ONCOLOGY Researchers at the University of Florida have created a point-of-care biosensor that can rapidly detect a biomarker for oral cancer. The device uses test strips, such as those used in blood glucose tests, to spot cell proliferation regulating inhibitor of protein phosphatase 2A (CIP2A), a protein biomarker that can...
KECK SCHOOL OF MEDICINE OF USC IMAGE: PICTURED IS AN ARTIST’S RENDERING OF CIRCADIAN CLOCK PROTEINS BMAL1 AND CLOCK INFLUENCING HEPATOCELLULAR CARCINOMA (HCC) CELL PROLIFERATION. THE STUDY SHOWS THAT IN HUMANS, HCC CELLS RELY ON BMAL1 AND CLOCK FOR SUSTAINED CELL GROWTH. TARGETING CLOCK PROTEINS PROVIDES A NEW PATHWAY TO DEVELOP NOVEL CANCER THERAPIES. CREDIT:...
by Melissa Rohman, Northwestern University Genetic relationships between IgA levels and human disease traits. a genome-wide genetic correlation analyses between IgA levels and autoimmune, infectious, and cardio-metabolic traits after exclusion of the HLA region (*P < 0.05; two-sided unadjusted P-values for genetic correlation by LD score regression). Supplementary Table 12 provides genetic correlations with and without HLA with...
by Bob Yirka, Medical Xpress Effect of NO in neural stimulation. a, Ca2+ influx fluorescence image of differentiated SH-SY5Y cells with Fluo-4 AM and nanogenerators (with and without BNN6) at 100 μg mL-1 concentration. The fluorescence image was taken 10 sec after the US treatment (10 sec, 0.4 W cm-2, Sonoporator, plane wave transducer module, 1 MHz,...
by Lisa M. Krieger, The Mercury News Credit: CC0 Public Domain Is an ancient compound the new “wonder drug”? Metformin, a common medication to control diabetes, has become the controversial darling of tech’s health-conscious digerati who are enticed by preliminary research suggesting it might help promote longevity, reduce dementia and prevent a whole host of other conditions—including,...
by Ludwig Institute for Cancer Research Graphical abstract. Credit: Cell Metabolism (2023). DOI: 10.1016/j.cmet.2022.12.003 A Ludwig Cancer Research study has discovered that the immune system’s surveillance of cancer can itself induce metabolic adaptations in the cells of early-stage tumors that simultaneously promote their growth and equip them to suppress lethal immune responses. Led by Ludwig Lausanne Associate Member Ping-Chih...
by Kelly Malcom, University of Michigan Schematic illustration of three working hypotheses. Hypothesis 1: Dimensions of consciousness are encoded in multiple neurofunctional dimensions of the brain. Hypothesis 2: Cortical gradients construct a virtual multidimensional space, in which canonical functional brain networks occupy characteristic positions. Hypothesis 3: Brain network functional geometry shapes dynamic brain states. Credit: Nature...
by The Francis Crick Institute Picture of a self-establishing community (SeMeCo), a yeast cell model used by researchers to study the exchange of metabolites between cells. Credit: Cell (2023). DOI: 10.1016/j.cell.2022.12.007, Licence CC-BY Scientists at the Francis Crick Institute have uncovered how, when young and old cells co-operate and exchange resources, this increases the lifespan of all the cells....
by Tina Adamopoulos, University of Toronto Credit: Unsplash/CC0 Public Domain New research from the University of Toronto is providing valuable insight into how the brain works to retain memory—and it could help treat patients with memory impairment. Alexander Barnett, an assistant professor in the department of psychology in the Faculty of Arts & Science, and a team...
by Imperial College London Schematic of the experimental outline and hypothesis showing skin biopsies at baseline and then 2, 4 and 6 months after hair transplantation. Credit: Caroline Brogan, Imperial College London In a new Imperial College London study involving three volunteers, skin scars began to behave more like uninjured skin after they were treated...
