by Cedars-Sinai Medical Center Performance characteristics of a deep learning model for predicting CAC using PLAX TTE videos when applied to a held-out test data set. Receiver operating characteristic and PR curves across different classification thresholds with AUC (95% CI) and F1 score for predicting (A) presence versus absence of CAC and (B) CAC score...
by King’s College London Credit: Pixabay/CC0 Public Domain New research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College London has established a blood-based test that could be used to predict the risk of Alzheimer’s disease up to 3.5 years before clinical diagnosis. The study, published in the journal Brain, supports the idea that components...
by University of Maryland School of Medicine Colorized electron micrograph showing malaria parasite (right, blue) attaching to a human red blood cell. The inset shows a detail of the attachment point at higher magnification. Credit: NIAID A monoclonal antibody treatment was found to be safe, well tolerated, and effective in protecting against malaria in a...
by Gina Mantica, Children’s Hospital Boston Lynn Aureli hopes to inspire others in her new position as an oncology nurse at Dana-Farber Cancer Institute. Credit: Michael Goderre, Boston Children’s Hospital As a child, Lynn Aureli didn’t know that a particular genetic change contributed to her acute myeloid leukemia (AML)—an alteration that eventually would help explain...
by Ingrid Fadelli, Medical Xpress Sounds evoke neural activity in visual cortex, which is explained by small, sound-triggered movements of the mouse. Credits: Bimbard et al., 2023 Recent studies have found that brain regions previously thought to only process a specific type of sensory stimuli, such as the visual cortex, can also be affected by...
Lorraine L. Janeczko, MPH January 25, 2023 People with untreatable dystrophic epidermolysis bullosa (DEB) may soon have access to an investigational gene therapy delivered in a topical gel that is currently under review by the US Food and Drug Administration (FDA). In a phase 3 study of patients with DEB, “we found that repeated topical application of B-VEC [beremagene geperpavec], an...
By Leo SandsJanuary 26, 2023 at 10:30 a.m. EST This tiny robot can melt, escape from a prison by sliding through secure bars, and then reform into a solid and complete tasks. The metal microbot, made out of liquid metal microparticles that can be steered and reshaped by external magnetic fields, has been widely compared...
