MAX PLANCK INSTITUTE FOR THE SCIENCE OF LIGHT IMAGE: THE TISSUE BIOPSY IS PROCESSED THROUGH A TISSUE GRINDER AND THEN ANALYZED USING REAL-TIME DEFORMABILITY CYTOMETRY (RT-DC). CREDIT: @ MARKÉTA KUBÁNKOVÁ – MAX-PLANCK-INSTITUT FÜR DIE PHYSIK DES LICHTS A team from the Max Planck Institute for the Science of Light (MPL) in Erlangen has created a...
Month: <span>April 2023</span>
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Balloon pulmonary angioplasty, a novel treatment for chronic blood clots in lung arteries, gives patients a new lease on life
TEMPLE UNIVERSITY HEALTH SYSTEM IMAGE: RIYAZ BASHIR, MD, FACC, PROFESSOR OF MEDICINE AND DIRECTOR OF VASCULAR AND ENDOVASCULAR MEDICINE IN THE SECTION OF CARDIOLOGY, DEPARTMENT OF MEDICINE, AT THE LEWIS KATZ SCHOOL OF MEDICINE AND TEMPLE UNIVERSITY HOSPITAL CREDIT: LEWIS KATZ SCHOOL OF MEDICINE AT TEMPLE UNIVERSITY Old blood clots in lung arteries can obstruct...
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Researchers identify promising new target for drug-resistant breast and ovarian cancers
by Lisa Marshall, University of Colorado at Boulder Graphical abstract. Credit: Molecular Cell (2023). DOI: 10.1016/j.molcel.2023.03.017 CU Boulder researchers have discovered a protein’s crucial role in helping breast and ovarian tumors survive and thrive and have found that suppressing that protein kills cancer cells without harming healthy ones. The findings, published Tuesday, April 12, in the journal Molecular...
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Long-term use of steroids could impair memory, study finds
by University of Bristol Methylprednisolone treatment desynchronizes hippocampal glucocorticoid receptor activity from endogenous master clock function. (A) Per1 mRNA expression in the SCN in CTL and MPL-treated rats. F1,28 = 83.97, P < 0.0001, for time by two-way ANOVA with Sidak’s post-hoc test. (B) Example locomotor activity in a CTL (blue) and a MPL (green)-treated rat. (C) CTL and MPL-treated rats maintained...
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Fwd: Brain-penetrating drug candidate found to be effective against deadly encephalitis viruses
by Will Cushman, University of Wisconsin-Madison This image shows a mouse brain cells infected with Venezuelan equine encephalitis virus, which is one of two viruses that cause encephalitis that are neutralized by a compound discovered by UW–Madison researchers. Credit: Dr. Yi Xue A new antiviral compound designed and synthesized by researchers at the University of Wisconsin–Madison’s...
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Whether physical exertion feels ‘easy’ or ‘hard’ may be due to dopamine levels, study suggests
by Johns Hopkins University School of Medicine Experimental paradigm. a Association phase; Participants were trained to associate between grip force exerted on a handheld dynamometer and effort levels from 0 to 100 (80% of maximum voluntary contraction (MVC)). Each trial began with presentation of the target, followed by an effortful grip with real-time visual feedback of...
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Selenium as a predictor of metabolic syndrome in middle-aged women
by Impact Journals LLC Credit: Unsplash/CC0 Public Domain A new research paper titled “Selenium as a predictor of metabolic syndrome in middle age women” has been published in Aging. Metabolic syndrome (MetS) is a widespread clinical entity that has become almost a global epidemic. Selenium plays an important role in metabolic homeostasis. It has been suggested that it...
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HIV, hepatitis B and hepatitis C can be detected from a single drop of blood, study shows
by European Society of Clinical Microbiology and Infectious Diseases Credit: Pixabay/CC0 Public Domain Data on a test that can detect HIV, hepatitis B and hepatitis C from a single drop of blood is being presented at this year’s European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) in Copenhagen, Denmark, (April 15–18). More than one million people...
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T cells: Vesicles strengthen immune response
by Ludwig Maximilian University of Munich MFG-E8-eGFP detects PS+ apoptotic and PS+ EV-decorated cells in vivo. Credit: Proceedings of the National Academy of Sciences (2023). DOI: 10.1073/pnas.2210047120 As a major component of the immune system, T cells play a critical role in fighting off viral infections. A team led by Prof. Thomas Brocker and Jan Kranich...
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‘Window into the brain’: A simple blood test to diagnose ALS is both robust and repeatable
by Brain Chemistry Labs Dr. Rachael Dunlop conducts real-time PCR on microRNA extracted from extracellular vesicles derived from blood samples from ALS patients. Credit: Paul Alan Cox, Brain Chemistry Labs ALS is a rare paralytic neurological disease that can impact people in the prime of life. Delays in receiving a definitive diagnosis can be devastating...