Month: <span>April 2023</span>

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Entering an ERA of 3D printing even for DNAs and proteins
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Entering an ERA of 3D printing even for DNAs and proteins

POHANG UNIVERSITY OF SCIENCE & TECHNOLOGY (POSTECH) IMAGE: 3D PRINTING OF BIOPOLYMERS (NUCLEIC ACIDS, POLYSACCHARIDES, PROTEINS) WITH NANOSCALE RESOLUTION CREDIT: POSTECH Three-dimensional (3D) bioprinting is a useful technique that has been widely utilized in our lives, ranging from reconstructive plastic surgery to artificial organ production. However, many biopolymers, such as nucleic acids, polysaccharides, and proteins,...

Low-cost sensor detects early-stage Parkinson’s disease in biological samples
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Low-cost sensor detects early-stage Parkinson’s disease in biological samples

FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO IMAGE: THE DEVICE, PRODUCED BY ORDINARY 3D PRINTING AND CAPABLE OF BEING MINIATURIZED, DETECTS LEVELS OF THE PROTEIN PARK7/DJ-1, WHICH IS ASSOCIATED WITH PARKINSON’S DISEASE CREDIT: CRISTIANE KALINKE AND PAULO ROBERTO DE OLIVEIRA Researchers at the University of Campinas (UNICAMP) and the Federal University of São...

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Taking a placebo improves adherence to treatment for opioid use disorder, study finds

UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE Substance use disorder affects 20 million Americans, and more than 100,000 people died from a drug overdose in 2021, according to the Centers for Disease Control and Prevention. While the medication methadone has the strongest evidence-based effectiveness to prevent relapse, about half of patients drop out of their treatment within...

New study flips the script on liver cancer
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New study flips the script on liver cancer

UNIVERSITY OF CALIFORNIA – SAN DIEGO IMAGE: UC SAN DIEGO SCIENTISTS FIND THE PROTEIN ATF4 PREVENTS LIVER DAMAGE AND ITS PROGRESSION TO CANCER BY BLOCKING FERROPTOSIS, AN IRON-DEPENDENT FORM OF LIVER CELL DEATH. CREDIT: UC SAN DIEGO HEALTH SCIENCES Liver cancer is the third leading cause of cancer death and the sixth most common cancer...

Mitochondria power supply failure may cause age-related cognitive impairment
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Mitochondria power supply failure may cause age-related cognitive impairment

by Salk Institute Electron microscopic image of neurons in the brain showing the presynaptic boutons (yellow), mitochondria (purple), and synapses (blue). Credit: Salk Institute Brains are like puzzles, requiring many nested and co-dependent pieces to function well. The brain is divided into areas, each containing many millions of neurons connected across thousands of synapses. These synapses,...

Key memory receptors are located on interneurons, finds study
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Key memory receptors are located on interneurons, finds study

by PNAS Nexus Hippocampal dorsal CA1 pyramidal neuron activity was captured using a head-mounted miniaturized endoscope. Contours of five cells are overlayed on the maximum projected image from a 10-minute recording; their associated fluorescence traces are shown below. Credit: Zhu et al A key receptor regulating memory formation has been localized to interneurons, according to...

Dual vaccine protects against two common food poisoning viruses
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Dual vaccine protects against two common food poisoning viruses

By Michael Irving April 11, 2023 Scientists may have a new weapon against the historically tricky-to-treat stomach bug norovirus Depositphotos If you’ve ever eaten something questionable and then paid for it from both ends for a few days, chances are you’ve had a norovirus. But this common pathogen is surprisingly tricky to treat or prevent....

New wrist sensor could save heart attack patients critical time in ER
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New wrist sensor could save heart attack patients critical time in ER

By Bronwyn Thompson April 12, 2023 The wrist sensor aims to detect high troponin levels within three to five minutes Dana Morse A new device designed to accurately and quickly sense whether a cardiac arrest patient also has a heart valve blockage that needs urgent treatment is now undergoing trials in Seattle. Cardiologists and emergency...

Blood-based markers may reveal Alzheimer’s disease ten years before symptoms show
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Blood-based markers may reveal Alzheimer’s disease ten years before symptoms show

by Karolinska Institutet Credit: CC0 Public Domain Alzheimer’s disease begins decades before the onset of any symptoms, such as memory loss. Consequently, early diagnosis increases the chances of slowing the disease down with drugs. A new study on an inherited form of the disease shows that a protein called GFAP is a possible biomarker for very...