Month: <span>April 2023</span>

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Simple, portable gadget could prevent misuse of everyday painkillers
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Simple, portable gadget could prevent misuse of everyday painkillers

By Bronwyn Thompson April 16, 2023 A new device can track drug levels for proper dosage Paulo Augusto Raymundo Pereira/FAPESP Acetaminophen (aka paracetamol) is a common go-to for treatment of acute pain like headache or toothache, and the popularity of such over-the-counter non-steroidal analgesics is clear, with around 60% of Americans having popped one of...

Treatment with immunotherapy alone produces ‘exceptional’ response rates in some melanoma patients
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Treatment with immunotherapy alone produces ‘exceptional’ response rates in some melanoma patients

by Ohio State University Medical Center Melanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0 Data from a national clinical trial shows that a striking 89% of patients with desmoplastic melanoma responded to immunotherapy (pembrolizumab) alone, suggesting that many patients could avoid the risk for toxicity from combination...

AI diagnoses lung disease based on X-rays
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AI diagnoses lung disease based on X-rays

by Skolkovo Institute of Science and Technology The first row contains lung X-ray images. The second row lists the diagnoses made by human radiologists. These are elaborated in the paragraphs provided in the third row. The bottom row contains comparable captions generated by the neural networks. The underlined fragments show that, while the text could clearly...

Depression found to affect the care and survival of patients with breast cancer
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Depression found to affect the care and survival of patients with breast cancer

by Wiley Credit: Unsplash/CC0 Public Domain In a recent study, having depression before or after a breast cancer diagnosis was associated with a lower likelihood of survival. The findings are published in the journal Cancer. For the study, Bin Huang, DrPH, of the University of Kentucky Markey Cancer Center, and his colleagues analyzed data from the Kentucky Cancer Registry...

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Should Race and Ethnicity Factor into Starting Ages for Mammography Screening?

Published on: April 20, 2023Jeff Hall Emerging research looking at data from over 414,000 cases of breast cancer deaths suggests that Black women should begin annual mammography screening seven to nine years earlier than White women. Could race and ethnicity-adapted starting ages for annual mammography screening have an impact in addressing disparities with breast cancer outcomes?...

Arthritis treatments: How to get pain relief from arthritis
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Arthritis treatments: How to get pain relief from arthritis

by Kirstie Ganobsik Credit: Unsplash/CC0 Public Domain There are more than 100 types of arthritis and related conditions, and they affect at least 54 million adults and 300,000 children in the United States, according to the Arthritis Foundation. Fortunately, there are also many medications, non-medication options, lifestyle changes and surgeries available to help you manage arthritis pain and other...

Surgery is the most effective treatment for metabolic liver disease, says new study
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Surgery is the most effective treatment for metabolic liver disease, says new study

by King’s College London Credit: CC0 Public Domain Metabolic (bariatric) surgery is more effective than medications and lifestyle interventions for the treatment of advanced non-alcoholic fatty liver disease. A new paper, published today in The Lancet by King’s College London and the Catholic University of Rome, is the first to compare three active treatments of non-alcoholic steatohepatitis (NASH) and to...

Blood tests may help physicians in low-resource environments diagnose Alzheimer’s disease
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Blood tests may help physicians in low-resource environments diagnose Alzheimer’s disease

by Columbia University Receiver Operator Curve Analyses of Plasma Biomarker Performance in Classifying Cerebrospinal Fluid (CSF)–Supported Diagnosis of Alzheimer Disease Performance of plasma biomarkers amyloid-β 1-40 (Aβ40) (inverse), amyloid-β 1-42 (Aβ42) (inverse), total tau (T-tau), neurofilament light chain (NfL), phosphorylated tau181 (P-tau181), and ratios of Aβ40/Aβ42, T-tau/Aβ42, and P-tau181/Aβ42 in classifying CSF biomarker (P-tau181/Aβ42)–supported diagnosis of...

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Is It Time to Stop Treating High Triglycerides?

Christopher Labos, MD CM, MSc March 29, 2023 Recent trial evidence has failed to show a cardiovascular benefit to treating high triglycerides. The publication of the PROMINENT trial, where pemafibrate successfully lowered high levels but was not associated with a lower risk for cardiovascular events, reinforced the point. Is it time to stop measuring and treating high triglycerides? Christopher Labos,...