Month: <span>April 2023</span>

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Adult-Onset ADHD: Treatment in Primary Care
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Adult-Onset ADHD: Treatment in Primary Care

Matthew F. Watto, MD; Paul N. Williams, MD DISCLOSURES March 24, 2023 Matthew F. Watto, MD: Welcome back to The Curbsiders. Today we’re going to be talking about attention-deficit/hyperactivity disorder (ADHD). We had a great guest, Dr Kevin Simon, who taught us all about this. Paul, is it possible for adults to develop ADHD de novo? Paul N. Williams, MD: I’m...

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COVID Can Mimic Prostate Cancer Symptoms

David King Keller, PhD DISCLOSURES March 20, 2023 If a patient’s prostate specific antigen (PSA) spikes 2 points in just 90 days, what is your first thought? This patient has a strong likelihood of aggressive prostate cancer, right? If that same patient also presents with severe, burning bone pain with no precipitating trauma to the area and...

Healthy adults don’t need annual COVID boosters, WHO advisers say
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Healthy adults don’t need annual COVID boosters, WHO advisers say

The advice clashes with FDA’s suggestion to treat COVID boosters like flu shots. BETH MOLE – 3/28/2023, 3:11 PM Enlarge / A vial containing Moderna COVID-19 booster vaccine at a vaccination center.Getty | SOPA Images147WITH A vaccine advisory group for the World Health Organization said Tuesday that, at this point, it does not recommend additional, let alone annual, COVID-19...

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New insights into an old drug: Scientists discover why aspirin works so well

AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY  IMAGE: RESEARCHERS HAVE MADE NEW DISCOVERIES ABOUT ASPIRIN’S MECHANISM OF ACTION AND CELLULAR TARGETS. THEIR FINDINGS SUGGEST POTENTIAL INTERPLAY BETWEEN CYCLOOXYGENASE ENZYME, OR COX, AND INDOLEAMINE DIOXYGENASES, OR IDOS, DURING INFLAMMATION. CREDIT: SUBHRANGSU MANDAL, UNIVERSITY OF TEXAS AT ARLINGTON New research has revealed important information about how aspirin...

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A New Approach to Type 2 Diabetes Management in Primary Care

Michael E. Bowen, MD, MPH, MSCS DISCLOSURES March 28, 2023 In the United States, primary care providers (PCPs) manage over 75% of patients with type 2 diabetes (T2D). Thus, PCPs are uniquely positioned to improve the glycemic control and cardiometabolic health of patients with T2D. In recent years, emerging data on the role of sodium-glucose cotransporter 2 (SGLT2) inhibitors and glucagon-like...

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CDC warns of drug-resistant, deadly fungus: How is it spread?

BY ALIX MARTICHOUX – 03/29/23 9:22 AM ET (NEXSTAR) – The Centers for Disease Control and Prevention has identified Candida auris as an “urgent” threat as it spreads rapidly through U.S. hospitals, tripling in just three years. The fungus is spreading “at an alarming rate,” the CDC says, but how exactly is it spreading? This fungus likely...

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An antibody-based drug triggers rare inflammatory eye problems in macular degeneration patients

by Delthia Ricks , Medical Xpress Neutralizing and non-neutralizing ADAs in complex with brolucizumab. A structural model of a complex comprised of one neutralizing anti-brolucizumab antibody in blue, and two non-neutralizing antibodies in light yellow. Brolucizumab is shown in gray, with the VEGF-A-binding CDRs highlighted in magenta. ADA, anti-drug antibody; CDR, complementarity-determining region; VEGF-A, vascular...

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Commotio Cordis Underrecognized, Undertreated Outside of Sports

Marilynn Larkin March 28, 2023 Sudden cardiac arrest (SCA) due to commotio cordis occurs more frequently in non-sport-related settings than is commonly thought, resulting in lower rates of resuscitation and increased mortality, especially among young women, a new review suggests. The condition is rare, caused by an often fatal arrhythmia secondary to a blunt, nonpenetrating impact over...