Matthew F. Watto, MD; Paul N. Williams, MD DISCLOSURES March 24, 2023 Matthew F. Watto, MD: Welcome back to The Curbsiders. Today we’re going to be talking about attention-deficit/hyperactivity disorder (ADHD). We had a great guest, Dr Kevin Simon, who taught us all about this. Paul, is it possible for adults to develop ADHD de novo? Paul N. Williams, MD: I’m...
COVID Can Mimic Prostate Cancer Symptoms
David King Keller, PhD DISCLOSURES March 20, 2023 If a patient’s prostate specific antigen (PSA) spikes 2 points in just 90 days, what is your first thought? This patient has a strong likelihood of aggressive prostate cancer, right? If that same patient also presents with severe, burning bone pain with no precipitating trauma to the area and...
Healthy adults don’t need annual COVID boosters, WHO advisers say
The advice clashes with FDA’s suggestion to treat COVID boosters like flu shots. BETH MOLE – 3/28/2023, 3:11 PM Enlarge / A vial containing Moderna COVID-19 booster vaccine at a vaccination center.Getty | SOPA Images147WITH A vaccine advisory group for the World Health Organization said Tuesday that, at this point, it does not recommend additional, let alone annual, COVID-19...
Nearly Half of Adults Over 40 May Have ‘Hidden’ Heart Disease: What to Know
A new study finds that many adults in the U.S. may have early signs of heart disease even if they don’t have any symptoms. Researchers found nearly half of adults in a study had signs of coronary heart disease or coronary atherosclerosis. Obstructive coronary atherosclerosis is associated with a more than 8-fold elevated risk for...
New insights into an old drug: Scientists discover why aspirin works so well
AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY IMAGE: RESEARCHERS HAVE MADE NEW DISCOVERIES ABOUT ASPIRIN’S MECHANISM OF ACTION AND CELLULAR TARGETS. THEIR FINDINGS SUGGEST POTENTIAL INTERPLAY BETWEEN CYCLOOXYGENASE ENZYME, OR COX, AND INDOLEAMINE DIOXYGENASES, OR IDOS, DURING INFLAMMATION. CREDIT: SUBHRANGSU MANDAL, UNIVERSITY OF TEXAS AT ARLINGTON New research has revealed important information about how aspirin...
A New Approach to Type 2 Diabetes Management in Primary Care
Michael E. Bowen, MD, MPH, MSCS DISCLOSURES March 28, 2023 In the United States, primary care providers (PCPs) manage over 75% of patients with type 2 diabetes (T2D). Thus, PCPs are uniquely positioned to improve the glycemic control and cardiometabolic health of patients with T2D. In recent years, emerging data on the role of sodium-glucose cotransporter 2 (SGLT2) inhibitors and glucagon-like...
CDC warns of drug-resistant, deadly fungus: How is it spread?
BY ALIX MARTICHOUX – 03/29/23 9:22 AM ET (NEXSTAR) – The Centers for Disease Control and Prevention has identified Candida auris as an “urgent” threat as it spreads rapidly through U.S. hospitals, tripling in just three years. The fungus is spreading “at an alarming rate,” the CDC says, but how exactly is it spreading? This fungus likely...
4 Foods That Spike the Same Weight Loss Hormone as Ozempic, Experts Say
ADDING THEM TO YOUR DIET COULD HELP YOU SHED POUNDS. By ELIZABETH LAURA NELSON MARCH 30, 2023 Freebird7977 / Shutterstock When it comes to weight loss, Ozempic is the name on everyone’s lips these days. Many people are taking the popular diabetes drug 0ff-label in hopes of reaching their goal weight—but some experts say that...
An antibody-based drug triggers rare inflammatory eye problems in macular degeneration patients
by Delthia Ricks , Medical Xpress Neutralizing and non-neutralizing ADAs in complex with brolucizumab. A structural model of a complex comprised of one neutralizing anti-brolucizumab antibody in blue, and two non-neutralizing antibodies in light yellow. Brolucizumab is shown in gray, with the VEGF-A-binding CDRs highlighted in magenta. ADA, anti-drug antibody; CDR, complementarity-determining region; VEGF-A, vascular...
Commotio Cordis Underrecognized, Undertreated Outside of Sports
Marilynn Larkin March 28, 2023 Sudden cardiac arrest (SCA) due to commotio cordis occurs more frequently in non-sport-related settings than is commonly thought, resulting in lower rates of resuscitation and increased mortality, especially among young women, a new review suggests. The condition is rare, caused by an often fatal arrhythmia secondary to a blunt, nonpenetrating impact over...