by Atrium Health Wake Forest Baptist Credit: CC0 Public Domain Wake Forest Institute for Regenerative Medicine (WFIRM) scientists have created a promising injectable cell therapy to treat osteoarthritis that both reduces inflammation and also regenerates articular cartilage. Recently identified by the Food and Drug Administration as a public health crisis, osteoarthritis affects more than 520...
BY ELISE OVERGAARD Misfolded proteins are toxic to cells. They disrupt normal functions and cause some age-related human degenerative diseases, like Alzheimer’s, Parkinson’s, and Huntington’s diseases. Cells work constantly to eliminate misfolded proteins, but these clearance mechanisms are still poorly understood. In a new study published April 20 in Nature Cell Biology, researchers at Stanford University discovered a previously unknown...
By Paul McClure April 20, 2023 Researchers have used gene therapy to develop a treatment for the damaging high intraocular pressure that is common in glaucoma Depositphotos The high eye pressure seen in glaucoma slowly leads to blindness. For some, the first-line treatment, eye drops, doesn’t work. Researchers have used gene therapy to develop a promising new...
by John H. Tibbetts, University of Georgia Anumantha Kanthasamy was recruited to UGA in 2021 as the inaugural John H. “Johnny” Isakson Chair and Georgia Research Alliance Eminent Scholar in Parkinson’s Research. After arriving in Athens, Kanthasamy immediately founded the Center for Neurological Disease Research and began building a network of faculty from around UGA to attack Parkinson’s and other neurodegenerative...
by Justin Jackson, Medical Xpress Graphical abstract of the study workflow and findings. Credit: Nature Microbiology (2023). DOI: 10.1038/s41564-023-01355-5 Published in Nature Microbiology, a study by researchers at the University of Copenhagen in Denmark has delved into the microbiota of patients with anorexia nervosa (AN) pathology and identifies the mechanistic interplay between restricted eating habits and how the gut microbiota’s...
It’s enough to disrupt an entire vacation and ruin exciting travel plans. Traveler’s diarrhea, the most common travel-related illness, is a gastrointestinal infection commonly caused by bacteria from contaminated food or water. In healthy adults, it’s typically an unpleasant inconvenience (to say the least) that clears up after a few days. But in infants and...
THE UNIVERSITY OF HONG KONG IMAGE: KNOCKOUT OF ANKLE1 INDUCES EXCESSIVE ACCUMULATION OF CYTOSOLIC DNA, LEADING TO ACTIVATION OF IMMUNE RESPONSES. CREDIT: DR GARY YING WAI CHAN AND DR HUADONG JIANG A research team led by Dr Gary Ying Wai CHAN from the School of Biological Sciences at The University of Hong Kong (HKU), has revealed the...
THE UNIVERSITY OF HONG KONG IMAGE: FABRICATION PROCESS OF THE ANISOTROPIC TENDON-MIMETIC HYDROGEL. CREDIT: THE UNIVERSITY OF HONG KONG Repairing or replacing injured tendons or similar load-bearing tissues represents one of the major challenges in clinical medicine. Natural tendons are water-rich tissues exhibiting outstanding mechanical strength and durability. Their mechanical properties originate from sophisticated microscale...
by Polly Tita, Rush University Medical Center Graphical abstract. Credit: JCI Insight (2023). DOI: 10.1172/jci.insight.166012 Scientists have uncovered a new understanding of how COVID-19 causes severe multi-organ injury in some patients and the pathways to stopping the cytokine storms behind them, according to new research published today in the Journal of Clinical Investigation Insight. “The research inspires a paradigm shift in how we think about...
LAURA SIMMONS Ideas that have been around for almost a century have been called into question by new research. Image credit: Sara Moser/Washington University The idea of a body-mind connection could have even more truth to it than you think. A new study has found evidence that the parts of the brain that control movement are...
