Month: <span>April 2023</span>

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US could soon approve MDMA therapy — opening an era of psychedelic medicine
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US could soon approve MDMA therapy — opening an era of psychedelic medicine

Sara Reardon Illustration by Adrià Voltà For Rick Doblin, 2023 could be a landmark year: the year that the US government decides whether it will allow the use of hallucinogenic drugs to treat mental illness. Doblin, who is based in Belmont, Massachusetts, is the founder and president of the non-profit organization Multidisciplinary Association for Psychedelic Studies...

Older adults may achieve same cognition as undergrads, shows new study
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Older adults may achieve same cognition as undergrads, shows new study

by J. D. Warren, University of California – Riverside Cognitive composite scores from Study 1 and Study 2. The dotted lines represent the means of cross-sectional convenience samples of younger (n = 28, Mage = 19.07 years, SDage = 1.05, range: 18–22), middle-aged (n = 22, Mage = 42.36 years, SDage = 5.79, range: 35–51), and older adults (n = 43, Mage = 70.17 years, SDage = 9.34, range: 53–89). The...

Biologists reveal a scissor enzyme that cuts the chromatin bridge and prevents DNA damage and autoimmunity
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Biologists reveal a scissor enzyme that cuts the chromatin bridge and prevents DNA damage and autoimmunity

by The University of Hong Kong Knockout of ANKLE1 induces excessive accumulation of cytosolic DNA, leading to activation of immune responses. Credit: Dr Gary Ying Wai Chan and Dr Huadong Jiang A research team led by Dr. Gary Ying Wai Chan from the School of Biological Sciences at The University of Hong Kong (HKU), has revealed...

Revolutionary Brain Tumor Treatment Discovered in Traditional Chinese Medicine
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Revolutionary Brain Tumor Treatment Discovered in Traditional Chinese Medicine

By BROWN UNIVERSITY APRIL 18, 2023 A new study has revealed the potential of a drug derived from indirubin, a natural compound used in traditional Chinese medicine, in treating malignant brain tumors in mice. Published in Cell Reports Medicine, the research highlights how a formulation of indirubin improved mice’s survival rates and moved the drug closer to clinical...

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Ozzy’s Wearable Cyborg May Be The Future of Physical Therapy

When Ozzy Osbourne canceled a tour this year due to health issues, his Instagram post cryptically mentioned the kind of treatment he’d received since a 2019 back injury and Parkinson’s disease diagnosis.  Osbourne, 74, said he’d had “groundbreaking Cybernics (HAL) Treatment,” medical technology developed in Japan that became available in the United States about 5 years ago.  The...

Bionic Finger ‘Sees’ Inside Objects by Poking Them
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Bionic Finger ‘Sees’ Inside Objects by Poking Them

A robotic finger’s supersensitive touches could probe inside body parts and circuits By Simon Makin on May 1, 2023 Scientific American May 2023 Issue Credit: Thomas Fuchs Human fingers don’t just sense what a surface feels like. They also tell us a lot about what’s underneath it: a really firm handshake, for example, can reveal...

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Single-Dose Psilocybin Promising for Resistant Depression

PARIS — A single 25-mg dose of a synthetic formulation of psilocybin appears to improve the core symptoms of treatment-resistant depression (TRD), a new analysis of phase 2 trial data suggests. Known as COMP360, the synthetic agent, a proprietary, purified form of psilocybin, improved symptoms related to mood and anhedonia while leaving aspects such as...

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RCSI study finds early signs that may help predict ADHD risk

RCSI Tuesday, 18 April 2023: Information available at birth may help to identify children with higher likelihood of developing ADHD, according to new research from RCSI University of Medicine and Health Sciences. The study, published in Development and Psychopathology, examined data from almost 10,000 children in the United States, showing information about pregnancy and birth may help to...

A new mechanism for crossing the blood–brain barrier
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A new mechanism for crossing the blood–brain barrier

by Lori Dajose, California Institute of Technology CA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified regions from WT/WT demonstrate endothelial expression across diverse brain regions. (B) AAV-PHP.eB, 9P31, and 9P36 packaging mNeonGreen under the control of the ubiquitous CAG promoter...