Month: <span>April 2023</span>

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New study challenges the idea that early Parkinson’s disease causes cognitive dysfunction
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New study challenges the idea that early Parkinson’s disease causes cognitive dysfunction

by Medical University of South Carolina Credit: Pixabay/CC0 Public Domain Like many neurodegenerative diseases, Parkinson’s disease (PD) is a thief that hacks into human operating systems and corrupts their cognitive hard drives until they can no longer control their movements or perform activities of daily living. Often, in its later stages, Parkinson’s disease steals data too,...

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Better blood sugar regulation

WILEY Patients with type 1 diabetes live with a constant risk of hyper- or hypoglycemia. Precisely controlled insulin release could help to improve regulation of their blood sugar levels. In the journal Angewandte Chemie, a research team has now introduced a novel insulin formulation that can be switched on by glucose: Lipid nanoparticle carriers release more...

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Smartwatches may be key to development of new Parkinson’s treatments

UNIVERSITY OF ROCHESTER MEDICAL CENTER New research shows that commercially available smartphones and watches, like the Apple Watch, are able to capture key features of early, untreated Parkinson’s disease.  These technologies could provide researchers with more objective and continuous ways to measure the disease and bring new treatments to market faster, particularly for patients in...

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Study describes mechanism that regulates activity of memory gene

FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO The protein PKMzeta is known to be associated with long-term memory formation. Neurological disorders such Alzheimer’s disease, as well as depression and aging, correlate with reduced levels of this protein in the brain. Researchers affiliated with institutions in Brazil and the United States have now...

Researchers develop new lower cost, dual-modality imaging technique to facilitate earlier disease detection
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Researchers develop new lower cost, dual-modality imaging technique to facilitate earlier disease detection

by Amber Rose, University of Illinois Grainger College of Engineering Photoacoustic image of a lymph node (top left), super-resolved vascular image (top right), dual photoacoustic super-resolution ultrasound image (bottom). Credit: The Grainger College of Engineering at the University of Illinois Urbana-Champaign Diagnostic imaging is indispensable in health care, as it allows clinicians to detect and diagnose...

Trim the sugar: New HIV vaccine design improves immune response
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Trim the sugar: New HIV vaccine design improves immune response

by The Scripps Research Institute A structural depiction of two HIV nanoparticle vaccines (E2p and I3-01v9) and a close-up of the Env proteins these nanoparticles display on their surfaces (HIV-1 BG505 UFO trimer). The vaccines are designed to have shorter sugars (or glycans) on the Env protein. Credit: Scripps Research A new HIV vaccine from Scripps Research has shown a significantly...

Increasing skeletal muscle mitochondrial efficiency after weight loss as a novel mechanism for lower energy expenditure
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Increasing skeletal muscle mitochondrial efficiency after weight loss as a novel mechanism for lower energy expenditure

HIGHER EDUCATION PRESS IMAGE: TLCL DEFICIENCY REDUCES OXPHOS EFFICIENCY. CREDIT: PATRICK J FERRARA, MARISA J LANG, JORDAN M JOHNSON, SHINYA WATANABE, KELSEY L MCLAUGHLIN, J ALAN MASCHEK, ANTHONY R P VERKERKE, PIYARAT SIRIPOKSUP, AMANDINE CHAIX, JAMES E COX, KELSEY H FISHER-WELLMAN, KATSUHIKO FUNAI Weight regains is a common problem for weight loss individuals. A number...

Study reveals the structure of the protein responsible for Huntington’s disease
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Study reveals the structure of the protein responsible for Huntington’s disease

by Spanish National Research Council Credit: Pixabay/CC0 Public Domain A team with the participation of researchers from the Institute for Advanced Chemistry of Catalonia (IQAC) of the Spanish National Research Council (CSIC) has revealed the structure of the protein responsible for Huntington’s disease, a severe neurodegenerative pathology characterized by the progressive disorder of movement and cognitive function. This research, published in the journal Nature...

Researchers discover molecular fail-safe that keeps bladder tissues from turning cancerous
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Researchers discover molecular fail-safe that keeps bladder tissues from turning cancerous

by Fred Hutchinson Cancer Center Credit: Pixabay/CC0 Public Domain Over the decades, scientists have revealed many strategies our cells use to keep normal cells from becoming cancerous. Now, Fred Hutchinson Cancer Center scientists have discovered a completely new—and counterintuitive—emergency brake that bladder cells use to stave off tumors even when cancer-promoting genes are turned on. In...

A renewable, engineered cell product shows potential for treating neurodegenerative and retinal diseases
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A renewable, engineered cell product shows potential for treating neurodegenerative and retinal diseases

by International Society for Stem Cell Research Graphical abstract. Credit: Clive Svendsen, Cedars-Sinai Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, USA Progressive loss of neurons is the underlying cause for a diverse spectrum of severe diseases called neurodegenerative diseases, which include Parkinson’s disease, amyotrophic lateral sclerosis (ALS) and retinitis pigmentosa. While strategies for regenerating...