By WEILL CORNELL MEDICINE MAY 13, 2023 A recent study using electronic health records from the National Institutes of Health’s RECOVER Initiative, analyzed the persistence of symptoms after SARS-CoV-2 infection (long COVID) among diverse populations in the United States. The findings emphasized the need for further investigation to improve the diagnosis and treatment of the disease. The...
by Jackie Maupin, Indiana University School of Medicine Credit: Unsplash/CC0 Public Domain Indiana University School of Medicine researchers studying clonal hematopoiesis of indeterminate potential (CHIP), a blood condition that may increase the risk of blood cancer, discovered that obesity was strongly associated with the condition. Their findings were recently published in the Journal of Clinical Investigation. CHIP...
by Compuscript Ltd Schematic diagram and pharmacokinetics of HER2-TP-cy5.5 and HER-TA-cy5.5 conjugate synthesis. (A) Schematic representation of the utilization of HER2-targeting peptide/antibody and Cyanine5.5-NHS ester (Cy5.5) to form conjugates. (B) Purification of the conjugates, (C) Collection of the purified components. (D) The circulation time of free Cy5.5 and Cy5.5-labeled peptide/antibody after intravenous injection in mice...
by Thamarasee Jeewandara , Medical Xpress Design of IL2-ep13nsEV and its utilization in treating breast cancer. To generate this active immunotherapy, the sEVs from autologous DCs are engineered with surface membrane–bound IL2 by expressing IL2-MFG-E8. This personalization of DC-derived sEV (p13nsEV) is achieved by loading lysed surgically harvested breast cancer cells onto engineered autologous DCs...
by Loretta Wylde, Monash University Wearable “skin” and biosensor. Credit: Monash University A new ultra-thin skinpatch with nanotechnology able to monitor 11 human health signals has been developed by researchers at Monash University. Researchers from the Faculty of Engineering and Faculty of Information Technology combined nanotechnology and artificial intelligence to bring machines one step closer to communicating with the human body. Using...
by Nagoya University High-quality 2D films could be one-drop away. Credit: Dr Minoru Osada A research group led by Professor Minoru Osada (he, him) and postdoctoral researcher Yue Shi (she, her) at the Institute for Future Materials and Systems (IMaSS), Nagoya University in Japan, has developed a new technology to fabricate nanosheets, thin films of two-dimensional materials a...
By some estimates, hearing loss affects at least 50% of the population after 75 years of age. While congenital hearing impairment—usually presenting in childhood—results from rare mutations, hearing problems in adults are likely due to the cumulative effect of polygenic risk and environmental factors. Recent genome-wide association studies have uncovered several risk genes implicated in...
Age-related macular degeneration is the leading cause of vision loss in Western countries. The condition, a deterioration of central vision, begins when droplets of lipids and proteins called lipofuscin accumulate in the retina and damage cells. Effective treatments for age-related macular degeneration (AMD) are not available and it remains unclear how healthy eyes prevent this...
MAY 19TH, 2023 CONN HASTINGS DIAGNOSTICS, MEDICINE, PEDIATRICS Student researchers at Rice University have developed a paper strip test for hypothyroidism, similar to those that are commonly used for COVID-19 testing. Babies with congenital hypothyroidism require prompt diagnosis and treatment, but in many parts of the world a lack of healthcare resources can mean that the condition...
LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN Biophysicists have designed a new cell-like transport system that represents an important milestone on the road to artificial cells. Creating artificial cells with life-like characteristics out of a minimal set of components is a major goal of synthetic biology. Autonomous motion is a key capability here, and one that is difficult to reproduce...
