by University of Edinburgh Receiver operating characteristic (ROC) curve analysis for the detection of colorectal cancer between cohorts. Area under the curve 0.85 (95% c.i. 0.80 to 0.90) for the single-fecal immunochemical test (FIT) cohort, 0.90 (0.87 to 0.93) for the first FIT analyzed (FIT1) of patients who completed at least one test and investigation in...
by University of Illinois at Chicago Credit: University of Illinois at Chicago With scarce clinical resources unable to keep pace with elevated rates of mental illness, technological solutions could help decrease waitlists and disparities in access to therapy. Recent advances in artificial intelligence have fueled interest in the use of chatbots and virtual assistants for mental...
by UT Southwestern Medical Center Credit: Pixabay/CC0 Public Domain A new type of developmental disability caused by mutations in a gene known as CBX1 has been discovered by a UT Southwestern Medical Center researcher and his colleagues. The findings, reported in Genetics in Medicine, offer insight into the role this gene plays in development and could eventually...
by Anna Megdell, University of Michigan Profiling of metabolite utilization in PDA cells identifies uridine. Credit: Nature (2023). DOI: 10.1038/s41586-023-06073-w Researchers at the University of Michigan Rogel Cancer Center have discovered a new nutrient source that pancreatic cancer cells use to grow. The molecule, uridine, offers insight into both biochemical processes and possible therapeutic pathways. The findings, published in...
by University of California, Los Angeles Description of agricultural pesticide use in the study area, including geography of applications, number of unique active ingredients applied by year, total pounds applied, and pesticide registration timeline. a) Geography of study region for PEG cohort and total pounds of pesticides applied in the region in 2000. Total pounds of...
by Swiss Tropical and Public Health Institute Male Trichuris trichiura. Credit: Leonardo M. Lustosa/Wikimedia Commons, CC BY-SA Soil-transmitted helminth infections are caused by different species of parasitic worms, including whipworms, hookworms and roundworms. Worldwide, more than 1.5 billion people are infected with at least one soil-transmitted helminth, with most of the infected population living in low- and...
by University of Montreal PNN components and metalloproteases are expressed by different cell types in mouse PFC. a Single cell RNA-sequencing (DropSeq) of PFC cells of P40-43 wild-type mice (n = 8 mice). t-SNE visualization of identified cell types; cluster 9 refers to PV+ cells. b–d Expression localization of critical components of PNN structure and remodeling, including lecticans (b...
by Jim Dryden, Washington University School of Medicine in St. Louis Using single-cell sequencing technology, diabetes researchers at Washington University School of Medicine in St. Louis have learned why islet beta cells produced from stem cells may not be as good at making insulin in response to blood sugar. The findings could improve treatment for those...
by Allessandra DiCorato, Broad Institute of MIT and Harvard Credit: Sonja Vasiljeva, Broad Communications Our bodies burn carbohydrates, proteins, and fat for fuel, and now, researchers at the Broad Institute of MIT and Harvard and the University of Lausanne have discovered another important energy source for cells: uridine, the chemical building block unique to RNA. Their new findings...
by Anthony King, Horizon: The EU Research & Innovation Magazine Around 6 million people in Europe suffer from epilepsy. Credit: © Madrolly, Shutterstock.com People with epilepsy could soon get a one-minute warning of an impending seizure with the help of a new medical device. An epileptic seizure can put a person at risk of injury in everyday situations that most...
