by University of Oslo Credit: Pixabay/CC0 Public Domain Sometimes scientists arrive at new findings and discoveries by chance. That was the case when Thilini Gamage was to carry out one of the studies in her doctoral work with Professor Eirik Frengen at the Institute of Clinical Medicine, University of Oslo. They study gene variation and mutations...
by Josep Carreras Leukaemia Research Institute NSUN7 epigenetic loss occurs in human primary HCC tumors in association with worse clinical outcome. (A) Percentage of NSUN7 methylation in the TCGA data set of primary tumors according to cancer type. (B) NSUN7 methylation is inversely correlated with NSUN7 transcript expression in TCGA HCC tumors. (C) NSUN7 methylation is...
by Massachusetts Institute of Technology Credit: Pixabay/CC0 Public Domain Inspired by sutures developed thousands of years ago, MIT engineers have designed “smart” sutures that can not only hold tissue in place, but also detect inflammation and release drugs. The new sutures are derived from animal tissue, similar to the “catgut” sutures first used by the ancient Romans....
New AI tools may aid the early diagnosis of Parkinson’s disease. Design by MNT; Photography by EDUARD MUZHEVSKYI/SCIENCE PHOTO LIBRARY/Getty Images Researchers developed an AI tool to predict Parkinson’s disease from blood samples. The tool can predict Parkinson’s 15 years before symptom onset with 96% accuracy. The underlying technology could possibly be adapted for diagnosing other conditions. Parkinson’s...
A clinical trial of an experimental universal influenza vaccine developed by researchers at the National Institute of Allergy and Infectious Diseases’ (NIAID) Vaccine Research Center (VRC), part of the National Institutes of Health, has begun enrolling volunteers at Duke University in Durham, North Carolina. This Phase 1 trial will test the experimental vaccine, known as...
Damian McNamara, MA May 11, 2023 CHICAGO — Anti-obesity medications and endoscopic sleeve gastroplasty (ESG) are popular strategies for weight loss on their own. Now researchers are looking at what happens when you combine them. In a study presented at Digestive Disease Week (DDW) 2023, they found ESG followed by an anti-obesity medication led to more total weight loss than...
By Andrew Joseph May 15, 2023 PET imaging of the brain of a man who appears to have been genetically protected against early Alzheimer’s.JUSTIN SANCHEZ For the second time in one extended family, researchers have identified a person who seemed genetically destined to develop early Alzheimer’s, but remained cognitively sound for several more decades. Like...
CHILDREN’S HOSPITAL OF PHILADELPHIA Philadelphia, May 17, 2023—Researchers at Children’s Hospital of Philadelphia (CHOP) and the University of California, Los Angeles (UCLA) have developed a computational platform capable of discovering tumor antigens derived from alternative RNA splicing, expanding the pool of cancer immunotherapy targets. The tool, called “Isoform peptides from RNA splicing for Immunotherapy target Screening”...
AMERICAN CHEMICAL SOCIETY Although diabetes is a common condition, no cure exists yet. Current therapies can manage blood sugar levels, but they do not address insulin resistance. But now, recent research reported in ACS Nano shows that targeting certain highly reactive molecules in the liver can reverse insulin resistance in human liver cells and diabetic...
UNIVERSITY OF HOUSTON IMAGE: WA XIAN, RESEARCH ASSOCIATE PROFESSOR AT THE UNIVERSITY OF HOUSTON STEM CELL CENTER AND FRANK MCKEON, PROFESSOR OF BIOLOGY AND BIOCHEMISTRY AND DIRECTOR OF THE CENTER, USED SINGLE CELL CLONING TECHNOLOGIES TO GENERATE LIBRARIES OF BASAL STEM CELLS FROM THE LUNGS OF 16 PATIENTS WITH IPF AND 10 PATIENTS WITHOUT THE...
