by Ten Bridge Communications Senolytics are an emerging class of investigational drug compounds that selectively kill aging-associated senescent cells (left, with red stain) without affecting other cells (right). Using artificial intelligence, researchers from Integrated Biosciences have, for the first time, identified three senolytics with comparable efficacy and superior drug-like properties relative to leading investigational compounds....
Peer-Reviewed Publication UNIVERSITY OF BASEL The hormone oxytocin is important for social interaction and to control emotions. A deficiency of this hormone has previously been assumed in various diseases such as autism, but has never been proven. Now, for the first time, researchers from the University of Basel and the University Hospital of Basel have...
by American Society for Biochemistry and Molecular Biology Enpp2 gene expression and autotaxin protein levels in jejunum. A. Enpp2 gene expression after feeding a chow diet (Chow) or Western diet (WD) for two weeks. Female Enpp2fl/fl/Ldlr-/- (Cont.) mice 3.1 ± 0.4 months of age (n = 5 mice per group) and female Enpp2fl/fl/Ldlr-/-/VilCre (iKO) mice 3.9 ±...
by Jocelyn Gecker A young couple sit on the beach in Huntington Beach, Calif., Monday, May 8, 2023. For years, studies have shown a decline in the rates of American high school students having sex. That trend continued, not surprisingly, in the first years of the pandemic, according to a recent survey by the Centers...
by Thamarasee Jeewandara, Medical Xpress Magnetic guidewire actuation concept at UHF inside an MRI scanner. (A) A clinical scenario of UHF actuation. The surgeon manually steers the guidewire using the magnetic fields inside the MRI scanner by observing real-time feedback from MRI images. (B to D) Guidewire bending by insertion to the MRI scanner for different magnetization...
by Ola Nilsson, Umea University Location of nursing homes, age and sex characteristics, and the progression of PCR-verified SARS-CoV-2 infections in the study population of 3012 study subjects. Panel A shows locations in Sweden of nursing homes with recruitment of study subjects in two metropolitan areas (Stockholm and Malmö; blue color) and three less densely populated...
by University of Tsukuba Credit: Sergey Nivens/Shutterstock Alzheimer’s disease (AD) is the most common form of dementia. It is important to start intervention from an early stage, e.g., the mild cognitive impairment (MCI) stage, to prevent or delay the progression of AD. For the early detection of AD and MCI, there is a growing need to...
EUROPEAN SOCIETY OF CARDIOLOGY Barcelona, Spain – 11 May 2023: Postmenopausal women with clogged arteries are at higher risk of heart attacks than men of similar age, according to research presented at EACVI 2023, a scientific congress of the European Society of Cardiology (ESC),1 and published in European Heart Journal – Cardiovascular Imaging.2 The study in nearly 25,000 adults...
AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY IMAGE: MICROSCOPY IMAGE OF A MOUSE AORTA WITH ATHEROSCLEROTIC LESIONS. PLAQUES ARE SHOWN IN RED. CREDIT: SRINIVASA REDDY In a recent study, researchers determined that derivatives of natural emulsifiers such as phospholipids found in high-fat, high-cholesterol diets can promote atherosclerosis via gut bacteria interactions with the immune system. This...
by Wolters Kluwer Health Graphical abstract. Credit: Journal of Urology (2023). DOI: 10.1097/JU.0000000000003397 For patients with kidney stones measuring one to two centimeters, a technique called mini-percutaneous nephrolithotomy (mini-PCNL) provides a higher stone elimination rate than another minimally invasive procedure called ureteroscopy (URS), concludes a randomized trial in the Journal of Urology. “In our clinical trial, mini-PCNL was more likely to...
