Daniel M. Keller, PhD May 09, 2023 Clinically important arrhythmias, especially nonsustained ventricular tachycardia (NSVT), may be more prevalent in patients with hypertrophic cardiomyopathy (HCM) than widely believed, suggests a study that questions current risk stratification practices in HCM. In the registry study, such arrythmias were observed in about six times as many HCM patients during 30...
Scientists release a new human ‘pangenome’ reference
by NIH/National Human Genome Research Institute Researchers have released a new high-quality collection of reference human genome sequences that captures substantially more diversity from different human populations than what was previously available. Credit: Darryl Leja, National Human Genome Research Institute, NIH Researchers have released a new high-quality collection of reference human genome sequences that captures substantially...
Osteoporosis and Osteopenia: Latest Treatment Recommendations
Neil Skolnik, MDD April 24, 2023 I’m Dr Neil Skolnik. Today’s topic is the new osteoporosis treatment guidelines issued by the American College of Physicians (ACP). The focus of the guidelines is treatment of osteoporosis. But first, I want to discuss screening. In their 2018 statement, the US Preventive Services Task Force (USPSTF) says that osteoporosis should be screened for in...
‘It’s still killing and it’s still changing.’ Ending COVID-19 states of emergency sparks debate
BY KAI KUPFERSCHMIDT, MEREDITH WADMAN World Health Organization Director-General Tedros Adhanom Ghebreyesus today declared an end to the COVID-19 Public Health Emergency of International Concern. CHRISTOPHER BLACK/WORLD HEALTH ORGANIZATION The World Health Organization (WHO) today declared an end to the emergency phase of the COVID-19 pandemic, days ahead of when a similar emergency in the...
Scientists raise concerns about popular COVID disinfectants
by Green Science Policy Institute Credit: CC0 Public Domain The COVID-19 pandemic has boosted the unnecessary use of antimicrobial chemicals linked to health problems, antimicrobial resistance, and environmental harm, warn more than two dozen scientists in Environmental Science & Technology. Their critical review details how quaternary ammonium compounds (QACs) are increasingly marketed and used in home,...
Medications Provide Best Risk-to-Benefit Ratio for Weight Loss, Says Expert
Christos Evangelou, MSc, PhD May 03, 2023 SAN DIEGO – For patients with obesity, surgery, lifestyle changes, and pharmacologic interventions are all treatment options, but antiobesity medications provide a better risk-to-benefit ratio, according to a presenter at the annual meeting of the American College of Physicians. Lifestyle changes result in the least weight loss and may be safest,...
New AACE Type 2 Diabetes Algorithm Individualizes Care
Miriam E. Tucker May 05, 2023 SEATTLE — The latest American Association of Clinical Endocrinology (AACE) type 2 diabetes management algorithm uses graphics to focus on individualized care while adding newly compiled information about medication access and affordability, vaccinations, and weight loss drugs. The clinical guidance document was presented May 5 at the AACE Annual Meeting 2023 and simultaneously published in Endocrine Practice. Using...
New Drugs in Primary Care: Lessons Learned From COVID-19
Christos Evangelou, MSc, PhD May 05, 2023 SAN DIEGO – A COVID-19 combination antiviral is the most important new drug primary care physicians have prescribed in recent years – plus it has helped keep many patients out of the hospital, according to a presenter at the annual meeting of the American College of Physicians. Nirmatrelvir-ritonavir was granted emergency use...
How epilepsy surgery is curing more seizures
by Kathy Katella, Yale University Lawrence Hirsch, MD, listens as Eyiyemisi Damisah, MD, reviews the plans for an upcoming epilepsy surgery. Credit: Anthony DeCarlo/Yale University More than ever before, people with epilepsy are living normal lives. The key is to get treatment, typically a medication, for seizures—the unpredictable disruptions in the brain’s electrical system that are...
Study shows melatonin, commonly used to improve sleep, can aggravate bowel inflammation
by Ricardo Muniz, FAPESP Melatonin (MLT) potentiates the acute inflammation in experimental colitis. Intestinal inflammation was induced by exposure to 3% dextran sulfate sodium (DSS) in drinking water for 7 days. (A) Mice were treated with MLT (10 mg/Kg) by gavage, from day 3 to 6, and euthanized on day 7 for sample collection (second experimental protocol)....