by Kyle B. Enfield, The Conversation Credit: Pixabay/CC0 Public Domain A patient of mine, once a marathon runner, now gets tired just walking around the block. She developed COVID-19 during the 2020 Christmas holiday and saw me during the summer of 2021. Previously, her primary care doctor had recommended a graded exercise program. But exercise exhausted...
The ability to chew properly may improve blood sugar levels in patients with type 2 diabetes
by Mary Durlak, University at Buffalo Post-operative panoramic X-ray; fixed implant-supported restoration. Credit: University at Buffalo If you’re a health care provider treating people with type 2 diabetes (T2D), University at Buffalo researcher Mehmet A. Eskan has this suggestion for you: check your patients’ teeth. In a study published in PLOS ONE on April 14, Eskan demonstrates that...
Diabetes drugs associated with fewer adverse cardiac events in older veterans
by Vanderbilt University Medical Center Credit: Pixabay/CC0 Public Domain GLP1 receptor agonists—a class of diabetes medications—are associated with fewer major adverse cardiovascular events than another type of diabetes drug (DPP4 inhibitors) in older veterans with no prior heart disease. The findings, reported in Annals of Internal Medicine, will aid clinicians in choosing a diabetes drug regimen for older...
Does your vaccine type matter in the battle against COVID?
by University of California, San Francisco Neutralizing antibodies (nAB) differed by vaccine type. A significant two-way interaction between time and vaccine type was identified. nAB increased over time for Janssen participants while decreasing over time for Moderna and Pfizer participants. At 6 months, Moderna was superior to Janssen, and both Moderna and Janssen were superior to Pfizer....
Autoimmune disorders found to affect around 1 in 10 people
by University of Oxford Credit: Shutterstock A new population-based study of 22 million people shows that autoimmune disorders now affect about 1 in 10 individuals. The work, published in The Lancet, also highlights important socioeconomic, seasonal, and regional differences for several autoimmune disorders and provides new clues on possible causes behind these diseases. Autoimmune diseases occur when the...
Traditional medicine plant could combat drug-resistant malaria
Peer-Reviewed Publication AMERICAN CHEMICAL SOCIETY IMAGE: THE LEAVES OF THE DWARF LABRADOR TEA PLANT CONTAIN AN OIL THAT COULD HELP FIGHT MALARIA. CREDIT: ADAPTED FROM ACS OMEGA, 2023, DOI: 10.1021/ACSOMEGA.3C00235 Much of what is now considered modern medicine originated as folk remedies or traditional, Indigenous practices. These customs are still alive today, and they could...
Atogepant Prevents Episodic Migraine in Some Difficult-to-Treat Cases
Jeff Craven April 27, 2023 CORRECTED May 4, 2023 // Editor’s Note: An earlier version of this article misstated the percentage of COVID-positive patients in the study population. BOSTON – Atogepant helped reduce the number of mean migraine days among adults with episodic migraine who failed multiple other oral migraine medications, according to findings from a study presented at the 2023 annual meeting of the...
New method enables detection of plasma biomarkers cheaply and at scale
by Nancy Fliesler, Children’s Hospital Boston Perchloric acid depletion workflow and method validation. (A) Workflow: PerCA plasma proteomic platform. (B) Principal components analysis to identify possible batch effects between phases 1 and 3 (colored in purple, pink, and brown) acquired over a 10-month period. (C) Sample-to-sample correlation of all reference plasma samples from the 44 plates....
Researchers solve mystery of how statins improve blood vessel health
by Nina Bai, Stanford Cardiovascular Institute Researchers at Stanford Medicine and their colleagues have discovered how statins improve cardiovascular health beyond lowering cholesterol. Credit: Roger Ashford/Shutterstock.com Using new genetic tools to study statins in human cells and mice, Stanford Medicine researchers and collaborators have uncovered how the cholesterol-lowering drugs protect the cells that line blood vessels....
Israeli researchers uncover indicator of accelerated cognitive decline in women with Alzheimer’s
By RENEE GHERT-ZAND 9 May 2023, 11:34 pm A team led by researchers at the Safra Center for Neuroscience and the Institute for Life Sciences at The Hebrew University of Jerusalem have uncovered a sex-specific molecular mechanism leading to more accelerated cognitive decline in women with Alzheimer’s disease than in men. Alzheimer’s, the leading cause of...