by Homa Shalchi, Baylor College of Medicine Engineered p16 epimutation recapitulates key features of age-associated epigenetic silencing. A p16 DNA methylation profiles in cis-MEF following serial passaging (p). A schematic of the p16 promoter of the cis-element knock-in allele with the CpG maps is shown. B Kinetics of p16 promoter methylation and mRNA expression in ctr-MEF and cis-MEF. Methylation levels were averaged from CpGs from − 814 bp to − 589 bp relative to the TSS....
by Simon Fraser University CC0/Pixabay Scientists at Simon Fraser University (SFU) and the Lankenau Institute for Medical Research (LIMR) near Philadelphia have found that a drug discovered at SFU and patented several years ago may have potential lifesaving results in the treatment of conditions leading to sudden cardiac death. The drug, known as AR-787, was originally discovered...
by Justin Jackson , Phys.org Allogeneic HIP islets achieve long-term survival. a, Immunofluorescence pictures of dissociated and reaggregated wtallo and HIPallo islets from rhesus monkeys (representative images). b, In vitro insulin secretion of wtallo and HIPallo islets (mean ± s.d., triplicates). c, The composition of wtallo and HIPallo islets of α, β, δ and other cells (mean, triplicates). d, Flow cytometry...
by Lourdes Medrano, AHA News Many Hispanic people in the United States face socioeconomic disadvantages and lower access to affordable health care. Despite these and other challenges to their health, they generally tend to live longer than other racial or ethnic communities—a health phenomenon that’s been studied for decades. The “Hispanic paradox” has been widely recognized...
Quantum laser-based technology a big step forward toward using exhaled breath to diagnose illness UNIVERSITY OF COLORADO AT BOULDER IMAGE: QIZHONG LIANG, A PHD CANDIDATE IN JILA AND THE DEPARTMENT OF PHYSICS AT THE UNIVERSITY OF COLORADO BOULDER, DEMONSTRATES HOW THE LASER-BASED BREATHALYZER WORKS, IN THE YE LAB AT JILA. ULTIMATELY, THE SYSTEM COULD BE...
The new graphene-based conductive hydrogel electrodes offer convenience of use, controllable degradation, and excellent signal transmission GIST (GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY) IMAGE: RESEARCHERS FROM GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (GIST), KOREA HAVE DEVELOPED GRAPHENE-BASED CONDUCTIVE HYDROGELS AS BIOELECTRODE MATERIALS FOR OVERCOMING THE CHALLENGES ASSOCIATED WITH TRADITIONAL, METAL-BASED BIOELECTRODES. THESE CONDUCTIVE HYDROGELS ARE...
Cima University of Navarra researchers show that smelling this substance modulates the immune system and improves cognition in animals with this neurodegenerative disease. This study opens the door to developing therapies based on stimulating and traini UNIVERSIDAD DE NAVARRA IMAGE: FROM LEFT TO RIGHT: CIMA UNIVERSITY OF NAVARRA RESEARCHERS MARÍA ALFARO, MARÍA ESPELOSÍN, MAR CUADRADO,...
Early studies suggest autologous serum tears are more effective at treating dry eye than other standard treatments. However, their effectiveness depends on the individual and the severity of their condition. Manufacturers make autologous serum tears, or autologous serum eye drops (ASEDs), from a person’s blood serum. They contain various vitamins, nutrients, and other growth factors...
May 11, 2023 The capsule collects bacteria and metabolites from the small intestine, not the lower colon Depositphotos In order to see what’s going on in someone’s digestive tract, doctors typically analyze stool samples obtained from that person. A new swallowable capsule, however, is claimed to paint a much more accurate picture of an individual’s...
By Paul McClure May 11, 2023 Research has found that there is a link between excess weight or obesity across life stages and an increased risk of GI cancer Depositphotos Overweight and obesity have been associated with many health problems, including cancer. A new study has found a link between excess weight and the risk of developing...
