GEORGIA INSTITUTE OF TECHNOLOGY IMAGE: AHMET F. COSKUN, A BERNIE MARCUS EARLY CAREER PROFESSOR IN THE COULTER DEPARTMENT OF BIOMEDICAL ENGINEERING AT THE GEORGIA INSTITUTE OF TECHNOLOGY AND EMORY UNIVERSITY CREDIT: GEORGIA TECH Organelles – the bits and pieces of RNA and protein within a cell – play important roles in human health and disease,...
The beginning is the end
MAX PLANCK INSTITUTE OF IMMUNOBIOLOGY AND EPIGENETICS IMAGE: EXAMPLE OF A GENE THAT CONTAINS TWO POSSIBLE START SITES (TSS), AND TWO POSSIBLE END SITES (TES). BLACK BOXES IN THE GENE MODEL SHOW SEQUENCES THAT WILL BE TRANSLATED INTO PROTEIN. WITH CONVENTIONAL SHORT-READ MRNA SEQUENCING, IN WHICH SIGNAL REPRESENTS THE ACCUMULATION OF READS, IT IS NOT...
Brain-altering fungi could lead the next frontier in mental health care
by Edel Hyland, The Conversation Fungal metabolites, such as psilocybin, may have therapeutic potential. Credit: Kyrylo Vasyliev/ Shutterstock If you were one of the millions of people who watched HBO’s TV series “The Last of Us,” you probably have a heightened awareness of the threat that fungi can have to our health. The series is set...
Strangely, cybersickness more likely to affect women, nobody knows why
Iowa State researchers in psychology and engineering found women experience cybersickness with virtual reality headsets more often than men. Their ongoing work, supported by a new $600,000 grant from the National Science Foundation, explores why this difference exists and options to help individuals adapt. Psychology professor Jonathan Kelly studies human-computer interaction, spatial cognition and virtual reality. He says gender discrepancies in cybersickness may...
High-Throughput Testing of Hundreds of Anti-Cancer Drug Combinations
MAY 11TH, 2023 CONN HASTINGS MEDICINE, ONCOLOGY Researchers at ETH Zurich in Switzerland have developed a high-throughput screening method for anti-cancer drugs that they have called “pharmascopy”. To date, the researchers have tested the system with multiple myeloma samples, a cancer that has a poor prognosis and is difficult to treat because of drug resistance. In such cancers, finding...
Study finds that when one eye is occluded, hearing improves almost immediately
by IMT School for Advanced Studies Lucca The illustration wants to suggest that the brain continuously adapts to cope with available visual inputs. Due to the strict interdependence between vision and audition, a change in the first affects the second, keeping the equilibrium between them. Credit: Carlo Gazzi The senses represent our gates to receive...
New therapy helps immune system eradicate brain tumors
by Swedish Research Council Graphical abstract. Credit: Cancer Cell (2023). DOI: 10.1016/j.ccell.2023.04.010 Researchers from Uppsala University have developed a method that helps immune cells exit from blood vessels into a tumor to kill cancer cells. The goal is to improve treatment of aggressive brain tumors. The study has been published in the journal Cancer Cell. Glioblastoma is an aggressive brain tumor that...
Survey of brain cell junctions shows striking similarities between schizophrenia and bipolar disorder
by Leah Eisenstadt, Broad Institute of MIT and Harvard Protein changes at brain cell synapses from patients with schizophrenia were strikingly similar to those from patients with bipolar disorder. Credit: Sonja Vasiljeva/Broad Institute Although bipolar disorder and schizophrenia are diagnosed as distinct psychiatric conditions, both are considerably heritable with molecular roots that are poorly understood. Some...
Improving the study of sex-based differences in complex traits and disease
by Melissa Rohman, Northwestern University Credit: Pixabay/CC0 Public Domain Phenotypic sex differences are common in many aspects of health and disease. Despite the success of genome-wide association studies in improving the understanding of how genetic variation contributes to the manifestation of complex traits or diseases, there has been little use of this data to investigate sex...
Study: Scarring of collagen ‘highway’ prevents stem cells from healing damaged tissue in Duchenne muscular dystrophy
by Holly Ober, University of California, Los Angeles Top, left: A healthy myoscaffold. Top right: A Duchenne muscular dystrophy scaffold. Bottom left: Stem cells (red) growing in a healthy myoscaffold (green). Bottom right: Stem cells growing in a Duchenne myoscaffold (green). Credit: Rachelle Crosbie Muscles that ache after a hard workout usually don’t hurt for long,...