by Serena Crawford, Yale University Uyen To, MD. Credit: Yale University Uyen To, MD, assistant professor of medicine (digestive diseases) and transplant hepatologist, discusses how she first became interested in studying Wilson disease, the wide spectrum of symptoms caused by the rare condition, and what’s next in this fascinating field of research. What is Wilson disease? Wilson...
AI found to perform better than humans in suggesting appropriate treatment steps in sepsis cases
by Vienna University of Technology A picture generated by an artificial intelligence showing how an AI in an ICU might look. Credit: Vienna University of Technology In the future, artificial intelligence will play an important role in medicine. In diagnostics, successful tests have already been performed: for example, the computer can learn to categorize images with...
Excitatory-inhibitory neurotransmitter imbalance precedes psychosis
by Elsevier Comparison between controls and deletion carriers, GABA+ and Glx levels in: a) Anterior cingulate cortex (ACC), b) Hippocampus and c) Superior Temporal Cortex (STC). Compared to controls, deletion carriers were found to have higher levels of Glx in the hippocampus and STC and lower levels of GABA+ in the hippocampus. The lines in the...
Molecular discovery may mean new treatments for rheumatoid arthritis
By Paul McClure May 11, 2023 When a person with rheumatoid arthritis receives healthy antibodies, it can reduce inflammation and bone degeneration. Researchers have, for the first time, discovered the molecular pathways that underlie this process Depositphotos Injecting antibodies from a healthy person into someone suffering from rheumatoid arthritis can reduce inflammation and slow bone...
Old motor neurons don’t die, scientists discover—they just slow down
by Joshua Speiser, Brown University Graphical abstract. Credit: JCI Insight (2023). DOI: 10.1172/jci.insight.168448 A new study led by researchers at Brown University’s Carney Institute for Brain Science offers a blueprint to help scientists prevent and reverse motor deficits that occur in old age. As humans age, tasks that require coordinated motor skills, such as navigating stairs or writing a letter, become...
Targeting uncontrolled inflammation may hold the key to treating therapy-resistant cancers
by Van Andel Research Institute Graphical Abstract. Credit: Molecular Cell (2023). DOI: 10.1016/j.molcel.2023.04.017 Van Andel Institute scientists have pinpointed how a specific gene mutation triggers an inflammatory cascade that may drive development of treatment-resistant cancers. The new findings, published today in Molecular Cell, reveal for the first time the molecular circuitry by which mutations in the gene STK11 cause inflammation to...
Researchers use generative AI to design novel proteins
Researchers at the University of Toronto have developed an artificial intelligence system that can create proteins not found in nature using generative diffusion – the same technology behind popular AI image-creation platforms such as Midjourney and OpenAI’s DALL-E. The system will help advance the field of generative biology, which promises to speed up drug development by making the design and testing of entirely...
Urine Test Could Reveal Cancer and Metastases
MAY 9TH, 2023 CONN HASTINGS DIAGNOSTICS, GENETICS, ONCOLOGY Researchers at MIT have developed a urine test that can distinguish between different types of cancer, and could even highlight if metastases are present. The test involves first administering nanoparticles to patients that can circulate around their blood before encountering a tumor. Enzymes that are overexpressed by the tumor...
Chest Wearable Provides Key Heart Measurements
MAY 10TH, 2023 CONN HASTINGS CARDIOLOGY Researchers at the University of Texas at Austin have developed a new chest wearable that can obtain both electrocardiogram and seismocardiogram data from the underlying heart. While basic ECG can be monitored via smart watches, no other wearable combines it with seismocardiography, which would conventionally be obtained by listening to the...
Our thoughts alter our tactile perception
RUHR-UNIVERSITY BOCHUM IMAGE: TWO NEEDLES OR JUST ONE? HOW WE PERCEIVE IT DEPENDS ON THE DISTANCE BETWEEN THE TWO NEEDLES. CREDIT: © RUB, NELLE Two needles feel like one The researchers measured the tactile perception of their 24 test participants using the two-point discrimination method. This involves the index finger lying relaxed on a device with two...