AI model spots those at highest risk for up to three years before diagnosis Peer-Reviewed Publication HARVARD MEDICAL SCHOOL An artificial intelligence tool has successfully identified people at the highest risk for pancreatic cancer up to three years before diagnosis using solely the patients’ medical records, according to new research led by investigators at Harvard...
Month: <span>May 2023</span>
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Detailed image of the human retina
Peer-Reviewed Publication ETH ZURICH IMAGE: DETAIL OF A CROSS-SECTION OF A RETINAL ORGANOID. DIFFERENT TISSUE STRUCTURES ARE MADE VISIBLE WITH DIFFERENT COLOURS. CREDIT: WAHLE ET AL. NATURE BIOTECHNOLOGY 2023 What cell types are found in which human tissue, and where? Which genes are active in the individual cells, and which proteins are found there?...
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How polycystic ovary syndrome can affect the health of future generations of men
by Karolinska Institutet Graphical Abstract. Credit: Cell Reports Medicine (2023). DOI: 10.1016/j.xcrm.2023.101035 Sons of women with polycystic ovary syndrome (PCOS) are three times more likely to develop obesity, according to a study published in Cell Reports Medicine. According to the researchers from Karolinska Institutet the findings highlight a previously unknown risk of passing PCOS-related health problems across generations...
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Mitochondrial ultrastructure regulated by calcium sensor, scientists at the Lewis Katz School of Medicine at Temple University discover
TEMPLE UNIVERSITY HEALTH SYSTEM (Philadelphia, PA) – Calcium homeostasis, involving the flow of calcium ions within cells, is essential for cell signaling and function. Importantly, calcium enters the cellular powerplants known as mitochondria, where it fine tunes energy production. Now, new research at the Lewis Katz School of Medicine at Temple University shows that, when it comes to...
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New Cleveland Clinic research links immune cell receptors to asthma, inflammatory lung disease
CLEVELAND CLINIC CLEVELAND – Inhibiting a protein on the surface of immune cells could offer new strategies for treating severe asthma, Cleveland Clinic researchers found. Researchers discovered a new way a protein called MCEMP1 contributes to severe inflammation in the airway and lungs. The discovery, published in Nature Communications, provides critical information for developing therapeutic interventions to treat long-term...
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Polycyclic aromatic hydrocarbons strongly linked to raised rheumatoid arthritis risk
by British Medical Journal Credit: Unsplash/CC0 Public Domain The amount of environmental exposure to polycyclic aromatic hydrocarbons, or PAH for short, is strongly linked to a person’s risk of developing rheumatoid arthritis, suggests research published in the open access journal BMJ Open. These chemicals, formed from the burning of coal, oil, gas, wood, or tobacco as well as the...
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Most antidepressants prescribed for chronic pain lack reliable evidence of efficacy or safety, scientists warn
by University of Southampton Credit: CC0 Public Domain Most antidepressants used for chronic pain are being prescribed with “insufficient” evidence of their effectiveness, scientists have warned. A major investigation into medications used to manage long-term pain has found that harms of many of the commonly recommended drugs have not been well studied. Published in the Cochrane Database...
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Oxygen therapy found to improve heart function in patients with long COVID
by European Society of Cardiology Credit: Pixabay/CC0 Public Domain A small randomized trial in patients with post-COVID syndrome has found that hyperbaric oxygen therapy promotes restoration of the heart’s ability to contract properly. The research is presented at EACVI 2023, a scientific congress of the European Society of Cardiology (ESC). “The study suggests that hyperbaric oxygen therapy can be beneficial...
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New research sheds light on how mesothelioma develops
by University of Maryland An asbestos fiber (stained blue) in lung tissue being surrounded by macrophages. Credit: Centers for Disease Control and Prevention Mesothelioma has been a high-profile disease at the center of several multibillion-dollar lawsuits, but the disease itself remains a medical mystery. The incurable cancer develops on the lining of many internal organs—including the...
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FDA-approved Alzheimer’s drug lecanemab could prevent free-floating amyloid beta fibrils from damaging the brain
by Cell Press Credit: Pixabay/CC0 Public Domain For the first time, researchers described the structure of a special type of amyloid beta plaque protein associated with Alzheimer’s disease (AD) progression. In a report published May 10 in the journal Neuron, scientists showed the small aggregates of the amyloid beta protein could float through the brain tissue fluid, reaching many...