SCRIPPS RESEARCH INSTITUTE LA JOLLA, CA—The insomnia drug suvorexant (Belsomra®) might be an effective treatment for opioid use disorder, according to a preclinical study from Scripps Research. In the study, published April 27, 2023, in Frontiers in Pharmacology, the Scripps Research scientists found that suvorexant reduced prescription opioid intake and helped protect against relapse in rats modeling opioid use...
Chinese medicine herb may have the power to help heart attack patients
by Newcastle University Credit: Pixabay/CC0 Public Domain A plant-based compound purified from the traditional Chinese herb, Astragalus, has the potential to improve the outcome of heart attack patients, new research has revealed. Experts at Newcastle University, UK, have found that the product, known as TA-65, significantly reduces inflammation and, unlike current cardiovascular treatments, does not negatively impact immunity....
Apple’s next big fitness feature could be an AI-powered coaching service
By Tom Pritchard published 1 day ago Apple could personalize your health fitness regime with AI(Image credit: Tom’s Guide)It seems every big tech company has some kind of plan for AI, and apparently Apple is no exception. According to Bloomberg’s Mark Gurman(opens in new tab), the company is working on a new health coaching service that...
System quickly spots antibiotic-resistant bacteria by watching them shimmy
By Ben Coxworth April 26, 2023 The ONMD setup (A) along with an optical image of E. coli bacteria (B) and that same view in which false colors highlight the movements of each bacterium (C)EPFL If the bacteria with which someone is infected are antibiotic-resistant, physicians need to know so as soon as possible, so...
KnitDema glove puts the electronic squeeze on swollen fingers
By Ben Coxworth April 26, 2023 The prototype hand-edema-treating KnitDema glove Cornell University Hand edema, which is a swelling of the fingers due to the accumulation of fluid from injury or disease, is typically treated via a hand massage performed by a therapist. A new finger-massaging glove, however, may offer a less costly and more...
Trial success for liver disease breath test
by University of Cambridge Credit: Owlstone Medical Cambridge-based company Owlstone Medical, co-founded by alumnus Billy Boyle, has experienced trial success for its liver disease breath test, following a study involving patients from Addenbrooke’s Hospital. Owlstone Medical is developing a non-invasive, easy-to-use breath test that can be taken in primary care settings for the diagnosis of advanced non-alcoholic steatohepatitis (NASH)—a...
New study questions the efficacy of many osteoarthritis treatments
LUND UNIVERSITY Please note: Comment pieces are written by experts in the field, and represent their own views, rather than necessarily the views of The Lancet or any Lancet specialty journal. Unlike Articles containing original research, not all Comments are externally peer reviewed. Recruiting osteoarthritis patients with a lot of pain to clinical studies, may give incorrect...
This killer protein causes pancreatic cancer
COLD SPRING HARBOR LABORATORY IMAGE: MOUSE PANCREAS CELLS WITH HIGH LEVELS OF THE PROTEIN SRSF1; CSHL PROFESSOR ADRIAN KRAINER FOUND THAT MICE WITH HIGH LEVELS OF SRFS1 TEND TO EXHIBIT INTRAEPITHELIAL NEOPLASIA—A KNOWN PRECURSOR TO THE MOST COMMON FORM OF PANCREATIC CANCER. CREDIT: KRAINER LAB/COLD SPRING HARBOR LABORATORY Pancreatic ductal adenocarcinoma (PDAC) is the most...
Arterial stiffness may cause metabolic syndrome in adolescents via an increase in fasting insulin and LDL cholesterol
by University of Eastern Finland The presence of any three of high blood pressure, high trunk fat mass, high fasting glucose, high fasting triglyceride and low fasting high-density lipoprotein cholesterol describes metabolic syndrome. Arterial stiffness in adolescents measured with carotid-femoral pulse wave velocity may potentially cause metabolic syndrome in young adulthood via an increase in fasting...
The antipsychotic clozapine linked to significantly less insomnia in people with schizophrenia
MEDICAL COLLEGE OF GEORGIA AT AUGUSTA UNIVERSITY IMAGE: DRS. BRIAN MILLER AND VAUGHN MCCALL CREDIT: AU PHOTOGRAPHER MICHAEL HOLAHAN. Insomnia affects up to half of people with schizophrenia and is thought to worsen the impact of their disease, including their risk of suicide. A new meta-analysis of the antipsychotics these patients take indicates those who...