by Delthia Ricks, Medical Xpress Antibody-mediated NK cell activity in children: (A) Merozoite opsonizing antibodies from Junju adults (n=40) induced a significantly higher proportion of ab-NK cells degranulation compared to Junju children (n=293). Hyperimmune (PHIS) and malaria naive plasma were included as positive and negative controls, respectively. Error bars represent a 95% confidence interval of...
SCIENTISTS MAY HAVE FIGURED OUT HOW TO REGENERATE LOST HEARING
GENETICS A team of Harvard Medical School scientists say they’ve come up with a new drug cocktail of molecules that they say can successfully regenerate the hair cells in the inner ear that enable hearing — a potentially groundbreaking treatment for hearing loss. As detailed in a new paper published in the Proceedings of the National Academy of Sciences,...
Cucumber-derived ingredient Q-actin supports joint function and mobility in clinical study
by Bentham Science Publishers Credit: Pixabay/CC0 Public Domain A new clinical study of adults with moderate joint health issues demonstrated that a novel iminosugar-containing dietary supplement ingredient, marketed as Q-actin , improved joint function and mobility significantly better than a placebo. The results were published in the February issue of Current Rheumatology Reviews. Q-actin is a...
Atrial fibrillation: Targeted drug therapy approach discovered for the first time
by Christine Vollgraf, Deutsches Zentrum für Herz-Kreislauf-Forschung e.V. Structured Graphical Abstract. Credit: European Heart Journal (2023). DOI: 10.1093/eurheartj/ehad086 When the heart gets out of rhythm, characteristic processes occur in the heart muscle cells. Among other things, the currents of electrically charged particles (ions) change. In chronic atrial fibrillation, one of these currents is reduced. Dr. Cristina Molina...
RNA editing guides immune cells to areas of tissue injury
by Eva Maria Wellnitz, Universitätsmedizin Mannheim Graphical Abstract. Credit: Immunity (2023). DOI: 10.1016/j.immuni.2023.03.021 A team of international scientists led by the Heidelberg University, Medical Faculty Mannheim, and the Newcastle University (Great Britain) has succeeded in decoding a new mechanism of immune cell trafficking by examining vascular diseases. Surprisingly, the fine-tuning of this fundamental immune defense process is...
Rapid Test for Mpox Virus Developed
APRIL 25TH, 2023 CONN HASTINGS DIAGNOSTICS, MEDICINE, PUBLIC HEALTH Researchers at Penn State have engineered a rapid testing technology for mpox, previously known as monkeypox. The mpox virus, which is transmitted through close contact with an infected person and that spread around the world last year, left healthcare staff grappling with a new problem. As the disease...
New insight into dying cells in Parkinson’s disease
UNIVERSITY OF SOUTHERN DENMARK When a patient experiences the first symptoms of Parkinson’s disease, the disease has been developing for a long time, and the patient may have already lost half of a specific type of nerve cells in the brain. Therefore, researchers are focused on understanding what happens to these brain cells before they become damaged...
Alzheimer’s Breakthrough? Common Sleeping Pill Reduces Levels of Disease Proteins
By WASHINGTON UNIVERSITY SCHOOL OF MEDICINE APRIL 24, 2023 A study at Washington University School of Medicine in St. Louis has shown that the FDA-approved insomnia medication suvorexant may reduce key Alzheimer’s proteins in the brain. Participants who took a higher dose of the drug experienced a significant drop in amyloid and hyperphosphorylated tau levels. However, the...
New smartphone app helps students with eating disorders at KU, with potential for broader reach
UNIVERSITY OF KANSAS IMAGE: RESEARCHERS AT THE UNIVERSITY OF KANSAS HAVE DEVELOPED A NEW APP THAT’S BEEN SHOWN ALREADY TO HELP STUDENTS LIVING WITH AN EATING DISORDER, ONE OF THE DEADLIEST MENTAL ILLNESSES. THE BEST-U APP’S USER INTERFACE INCLUDES VIDEOS, INTERACTIVE QUIZZES, SHORT QUESTIONS AND SURVEYS TO TRACK PROGRESS EACH WEEK. CREDIT: KELSIE FORBUSH LAWRENCE...
Near-universal T cell immunity towards a broad range of bacteria
MONASH UNIVERSITY IMAGE: IN THE IMAGE, THE PNEUMOCOCCI LIE IN THE BACKGROUND, AN ARRAY OF MACROPHAGES AND DENDRITIC CELLS ARE ARRANGED AROUND THE CENTRAL IMAGE OF A T CELL. ROWS OF TCRS INTERACTING WITH THE IDENTIFIED PNEUMOLYSIN EPITOPE BOUND TO HLA (WHITE) CROSS THE LENGTH AND BREADTH OF THE ARTWORK, EMPHASISING THEIR CENTRALITY IN THE...