Joseph Prezioso Thousands of people say they’ve developed tinnitus after they were vaccinated against Covid. While there is no proof yet that the vaccines caused the condition, theories for a possible link have surfaced among researchers. Shaowen Bao, an associate professor in the physiology department of the College of Medicine at the University of Arizona, Tucson,...
MASSACHUSETTS INSTITUTE OF TECHNOLOGY IMAGE: MIT ENGINEERS HAVE DESIGNED A NEW NANOPARTICLE SENSOR THAT CAN ENABLE CANCER DIAGNOSIS WITH A SIMPLE URINE TEST. THE NANOPARTICLES (BLUE) CARRY DNA BARCODES (ZIGZAG LINES) THAT CAN BE CLEAVED BY CANCER-ASSOCIATED PROTEASES IN THE BODY (PAC-MAN SHAPES). ONCE CLEAVED, THE DNA BARCODES CAN BE DETECTED IN A URINE SAMPLE....
by Cedars-Sinai Medical Center Credit: Pixabay/CC0 Public Domain The first prospective study comparing outcomes in patients with pituitary apoplexy—sudden bleeding or death of a pituitary tumor—found that patients managed medically fared as well as those treated surgically in the majority of cases. The multicenter international study, led by Cedars-Sinai investigators, was presented today (April 24) at...
by Weill Cornell Medical College The cGAS–STING pathway is activated in the hippocampi of mice with tauopathy and in human AD brains. Credit: Nature Neuroscience (2023). DOI: 10.1038/s41593-023-01315-6 Targeting part of an antiviral pathway triggered by the accumulation of a key pathogen shared in Alzheimer’s disease and frontotemporal dementia may one day offer a new therapeutic approach to...
by Cochrane Reviews Illustration of bacteria in the human gut. Credit: Darryl Leja, National Human Genome Research Institute, National Institutes of Health A new study, published in the Cochrane Database of Systematic Reviews and led by an Upstate Medical University professor, has found that compared with standard antibiotic treatment, stool transplantation can increase the number of people recovering from...
by Liu Jia, Chinese Academy of Sciences Credit: Pixabay/CC0 Public Domain In a study published online in the Schizophrenia Bulletin, researchers from Dr. Wang Wei’s lab at the Center for Excellence in Brain Science and Intelligence Technology of the Chinese Academy of Sciences, and Dr. Wang Jijun’ team at Shanghai Mental Health Center, Shanghai Jiao Tong University School of...
April 24, 2023 07:00 AM EDTUpdated 09:16 AM R&DPharmaAstraZeneca, Ionis unveil full PhIII data for ‘mega brand’ ATTR drugMax GelmanSenior EditorAstraZeneca and Ionis fleshed out a Phase III win for eplontersen Monday morning at this year’s American Academy of Neurology meeting, illustrating why the pair is so confident in its potential success. Eplontersen all but...
Problems with a sense of smell may predict a higher risk for age-related health problems, according to researchers from the Department of Otolaryngology–Head and Neck Surgery, Johns Hopkins University School of Medicine. What to Know Smell dysfunction acts as an early indicator of cognitive decline as well as signs of frailty in the brain and unhealthy aging. Researchers assessed olfactory sensitivity and olfactory identification, terms...
by King’s College London CSPG4 expression in malignant melanoma and normal tissues. a CSPG4 mRNA expression, derived from RNAseq data, across cell lines of different cancer cell types. n represents the number of cell lines (data from Cancer Cell Line Encyclopedia (CCLE), portals.broadinstitute.org/ccle, n = 56, n = 59, n = 26, n = 57, n = 28, n = 27, n = 48, n = 127, n = 41, n = 32, n = 26, n = 37, n = 8, n = 50, and n = 58, respectively) (p = 0.0156 and p ≤ 0.0001). b CSPG4 gene expression in tissues across cancer types (data and images from Human Protein...
by Diana Yates, University of Illinois at Urbana-Champaign In a study of older adults, a research team led by, from left, Christopher Zwilling, Tanveer Talukdar and Aron Barbey found that blood markers of two saturated fatty acids, along with certain omega-6, -7 and -9 fatty acids, correlated with better scores on tests of memory and were associated with...
