by Will Sansom, University of Texas Health Science Center at San Antonio Credit: Pixabay/CC0 Public Domain The Mays Cancer Center at The University of Texas Health Science Center at San Antonio recently conducted a clinical trial combining two drugs in patients with recurrent, high-grade glioblastoma (GBM). The Mays Cancer Center, one of the four National Cancer...
by CU Anschutz Medical Campus Differential expression levels of CaMKII tool mutants in HEK293 cells. Credit: Journal of Biological Chemistry (2023). DOI: 10.1016/j.jbc.2023.104693 A promising new stroke drug that temporarily inhibits a key protein in the brain without causing lasting harm may significantly change the future treatment of cerebral and global ischemia, according to a new study by...
by European Stroke Organization Conference Credit: CC0 Public Domain A team of researchers from Denmark has developed a new artificial intelligence (AI) framework to address the number of strokes that go unrecognized by human emergency call handlers. The framework outperformed emergency call handlers in recognizing stroke for both sexes and across all age groups studied, indicating its...
by University College London Credit: Unsplash/CC0 Public Domain The biology underpinning a rare genetic mutation that allows its carrier to live virtually pain-free, heal more rapidly and experience reduced anxiety and fear, has been uncovered by new research from UCL. The study, published in Brain, follows up the team’s discovery in 2019 of the FAAH-OUT gene and the...
by University of Gothenburg The researchers’ molecule Z4P inhibits one of the mechanisms that regulate protein production in a cancer cell. This inhibition causes the cancer cell to die. Three pictures show the spread of the tumor after 20 days of treatment on mice. Control: Untreated tumor. TMZ: Follow-up treatment solely with chemotherapy. Combo: Combination treatment with...
by American Heart Association Credit: Pixabay/CC0 Public Domain A study of more than 58,000 women over a 12-year period found that longer or shorter menstrual cycles were associated with a higher risk of developing cardiovascular disease, heart attack or atrial fibrillation, according to new research published in the Journal of the American Heart Association. Regular menstrual cycle length, defined as cycle...
by Kim Krieger, University of Connecticut Schematic of fabrication process of anatomically shaped scaffolds from rabbit radius bone. Credit: Proceedings of the National Academy of Sciences (2023). DOI: 10.1073/pnas.2219756120 Repairing severely damaged bones is a challenge—especially the long bones of the arms and legs. Now, UConn Health scientists describe a new method in the May 22 issue of...
by University College London Credit: Pixabay/CC0 Public Domain Research led by UCL, in partnership with the MRC Laboratory of Molecular Biology (MRC LMB) and AstraZeneca, has identified a new compound that can stimulate nerve regeneration after injury, as well as protect cardiac tissue from the sort of damage seen following a heart attack. The study, published in Nature,...
by University of Florida A “fishing hook” molecule in red is added to a drug-like compound to catch enzymes that chop up RNA, yellow, for recycling by cells. The strategy has been used to break up oncogenes known for causing some of the most dangerous, untreatable cancers. Credit: Disney lab at The Wertheim UF Scripps Institute....
by Ludwig Maximilian University of Munich Study overview, upper airways viral loads, and antibody-mediated neutralization of SARS-CoV-2. a Schematic representation of the study design. Donors were sampled weekly for 1 month and then periodically until 6 months after initial presentation. b Longitudinal quantification of upper airways viral loads (UA-VLs) in patients with mild COVID-19 (n = 25) recruited during the first week...
