REGENSTRIEF INSTITUTE INDIANAPOLIS – Colorectal cancer incidence and deaths are declining for individuals age 50 and older, but are increasing for those under 50. A new study, led by researcher-clinician Thomas Imperiale, M.D., of the U.S. Department of Veterans Affairs, Regenstrief Institute and Indiana University School of Medicine, identifies seven risk factors for early onset...
Month: <span>July 2023</span>
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Body’s immune response may offer alternative approach to neuropathic pain therapies
CELL PRESS IMAGE: THIS DIAGRAM SHOWS HOW NK CELL FUNCTION COULD IN THEORY RESULT IN THE RESOLUTION OF NEUROPATHIC PAIN IN THE CONTEXT OF PERIPHERAL NERVE INJURY BY DIRECTED CYTOTOXICITY AGAINST A NUMBER OF PATHOLOGICAL CELLULAR TARGETS. CREDIT: KIM ET AL./TRENDS IN NEUROSCIENCES In the midst of a global opioid epidemic, a team of scientists...
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Follow the leader: Researchers identify mechanism of cancer invasion
PENN STATE IMAGE: A PENN STATE-LED RESEARCH TEAM FOUND THAT A MOLECULE CALLED MALAT1 HELPS REGULATE THE CELLS THAT LEAD CANCER INVASION. THE TOP ROW SHOWS BLADDER CANCER CELLS WITH MALAT1 EXPRESSION, WHILE THE BOTTOM ROW SHOWS BLADDER CANCER CELLS WITH REDUCED MALAT1 EXPRESSION. IN THE TOP ROW, THE CELLS ARE BEGINNING THEIR MIGRATION AWAY...
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Penn State researchers develop digital test to directly measure HIV viral load
PENN STATE IMAGE: IN THE NEW QUANTIFICATION METHOD DEVELOPED BY PENN STATE RESEARCHERS, A MOLECULAR SIGNAL SHINES GREEN WHEN HIV IS DETECTED IN AN RNA MOLECULE. BY COUNTING THE SIGNALS, RESEARCHERS CAN QUANTIFY THE VIRAL LOAD IN A SAMPLE. CREDIT: PROVIDED BY WEIHUA GUAN UNIVERSITY PARK, Pa. — A milliliter of blood contains about 15...
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Researchers discover how an infectious parasite uses immune cells as a Trojan Horse
by University of Calgary Leishmania parasites are carried by sand flies. Credit: Pauline Zulueta, Cumming School of Medicine University of Calgary researchers have discovered how Leishmania parasites hide within the body to cause Leishmaniasis. The tiny parasites are carried by infected sand flies. Considered a tropical disease, 1 to 2 million people in more than 90 countries are...