by Laurie Fickman, University of Houston (A) Fully assembled one-size-fit-all (patent pending) headset design. (B) Dry-electrode bracket. (C) The skin sensor holder. This figure was adapted from US provisional patent #62857263. Credit: Sensors (2023). DOI: 10.3390/s23135930 The world of at-home stroke rehabilitation is growing near, incredible news for the 795,000 people in the United States who annually suffer...
Inhibiting NLRP3 signaling in aging podocytes improves longevity
by Impact Journals LLC Podocyte inflammaging is reduced by inhibiting NLRP3. Credit: Aging (2023). DOI: 10.18632/aging.204897 A new research paper titled “Inhibiting NLRP3 signaling in aging podocytes improves their life- and health-span” has been published in Aging. The decrease in the podocytes’ lifespan and health span that typify healthy kidney aging cause a decrease in their normal structure, physiology and...
The temperature the human body cannot survive
by Daniel Lawler One recent case of extreme heat threatening health came at a jamboree in South Korea, where hundreds of scouts fell ill. Scientists have identified the maximum mix of heat and humidity a human body can survive. Even a healthy young person will die after enduring six hours of 35-degree Celsius (95 Fahrenheit)...
Secretome mass spectrometry approach uncovers blood-brain barrier mystery
by Universitätsklinikum Bonn In the microscope image, astrocytes are stained green and immune cells are stained red. The basement membranes of the vessels are seen in white. Credit: University of Münster / University Hospital Bonn (UKB) Researchers have identified novel gelatinase substrates involved in astroglial barrier function. In neuroinflammation, immune cells such as leukocytes cross the...
First experiments with carbon black pigment dispersion acting as a Janus ultrasound contrast agent
by Compuscript Ltd Normalized mean grayscale backscattered intensity of brightness-mode ultrasound images (A, B) of a tissue-mimicking phantom receptacle with a cylindrical well filled with undiluted pigment dispersion, as a function a time (C). Timestamps are shown at the top right. Credit: BIO Integration (2023). DOI: 10.15212/bioi-2023-0004 Theranostic ultrasound contrast agents comprise a therapeutic component whose controlled...
Research suggests a new approach for treatment-resistant breast cancers
by Louisiana State University CB-103 shows synergy with paclitaxel and fulvestrant in breast cancer cell lines. TNBC (HCC1187) and ER+ BC (MCF-7) cells were treated with combinations of CB-103 (150 nM–10 μM) with paclitaxel or fulvestrant (75 nM–20 μM) and cell viability was measured after 72 h of treatment. Synergy between CB-103 and paclitaxel or fulvestrant...
First-Ever Vaccine Candidate Against Epstein-Barr Delivers Promising Results
09 August 2023 By DAVID NIELD The vaccine counters the virus and stops it evolving. (QIMR Berghofer Medical Research Institute) Researchers have made a significant breakthrough in the development of the first-ever vaccine for the Epstein-Barr virus (EBV), a virus that causes infectious mononucleosis (IM, or ‘mono’) – also known as glandular fever. The virus can infamously lead to further health issues like cancer and multiple sclerosis (MS)....
Scientists begin to untangle how COVID-19 affects brain cells
by The Francis Crick Institute Astrocytes, endothelial cells, pericytes and microglia expression of ‘entry factors’ (ACE2, TMPRSS2, NRP1 and CD147) which are receptors in the cells that the COVID-19 virus uses to enter, as shown by the colors in the image. Credit: Alize Proust, Journal of Neuroinflammation Researchers at the Francis Crick Institute have shown in lab-based...
A new clue to the reason some people come down with long COVID
August 8, 2023 10:06 AM ET Max Barnhart Protesters march outside the White House to call attention to those who have long COVID. Nathan Posner/Anadolu Agency via Getty Images Stéphanie Longet is an immunologist and a COVID researcher at the University of Saint-Etienne in France, and just like 10-20% of adults who were infected with the...
Hope for type 2 diabetes sufferers with the electric zap that could END insulin jabs for sufferers
By RACHEL ELLIS UPDATED: 18:40 EDT, 7 August 2023 A new one-hour procedure could mean an end to daily insulin jabs for thousands of people with type 2 diabetes. While insulin jabs can control the condition, they may be uncomfortable and need to be administered regularly, after careful calculations. Now scientists have discovered that zapping the lining of...