New research in mice suggests a bodybuilding supplement may be able to improve memory. Kseniya Ovchinnikova/Getty Images Researchers investigated the effects of the bodybuilding supplement HMB on Alzheimer’s disease markers in mice. HMB improved cognitive ability and reduced the buildup of amyloid plaques in mouse models of Alzheimer’s. Further studies are needed to see how these findings...
By Neha Mathur Aug 8 2023 Reviewed by Lily Ramsey, LLM In a recent article published in the Biologics Journal, researchers examined de-identified clinical data to identify gene fusions by next-generation deoxy- and ribonucleic acids (DNA and RNA) sequencing to understand their relationship with observed pathologies in a diverse population of cancer patients. Study: Precision Medicine...
TECHNICAL UNIVERSITY OF MUNICH (TUM) Overly active immune cells are often behind lung damage in diseases such as Covid-19. Researchers at the Technical University of Munich (TUM) have developed an RNA agent for a lung spray that slows the activity of these cells, known as macrophages. A new, sugar-based transport mechanism is especially effective in bringing the...
By Paul McClure August 08, 2023 Researchers have developed an injectable form of DHA, an omega-3 fatty acid, that is more effective than its oral counterpart Depositphotos Researchers have developed an injectable form of DHA, an omega-3 fatty acid, that is effective in halting the progression of the arterial fatty plaques that can lead to heart...
by Emily Moskal, Stanford University Imaging approach for the detection of activated peripheral CNS-infiltrating myeloid cells. Peripheral myeloid cells (monocytes, macrophages, neutrophils, and dendritic cells) are recruited to the central nervous system (CNS) during multiple sclerosis (MS). Peripheral myeloid cells, in addition to brain resident microglia, are associated with CNS MS lesions and are fundamental to...
by University of Basel Clinical Characterization of Patients Seropositive for Myelin Oligodendrocyte Glycoprotein (MOG) Immunoglobulin (Ig) A A, Frequency of disease manifestations for patients with isolated MOG-IgA and MOG-IgG. B, Frequency of positive and negative cerebrospinal fluid (CSF)–specific oligoclonal bands (OCBs) in MOG-IgA seropositive multiple sclerosis (MS) compared with seronegative MS. C, Magnetic resonance imaging (MRI)...
by Institute for Systems Biology Graphical Abstract. Credit: Cell Reports (2023). DOI: 10.1016/j.celrep.2023.112875 Mycobacterium tuberculosis (Mtb) is the pathogen that causes tuberculosis (TB), the world’s deadliest infectious disease. Mtb is so successful and harmful because it can adapt to different conditions inside our bodies, allowing it to evade treatment. By using a computer model to understand Mtb’s...
by Pasteur Institute Antibody fragments of EPCT112 bNAb (blue) discovered at the Institut Pasteur by Hugo Mouquet’s team, here forming a complex with the HIV-1 envelope protein (Env) (shown in yellow and orange). Credit: (c) Institut Pasteur / Hugo Mouquet Some HIV-1 carriers who have received an early antiretroviral treatment during several years are able to...
by Science China Press In this study, researchers provided a single-cell transcriptomic landscape of mouse ovarian mesenchymal cells and analyzed the cellular and molecular changes of ovarian stroma cell during reproductive aging. Based on bioinformatics analysis, the team provided an interested anti-reproductive aging strategy by improving the quality of ovarian stroma cells in the aged ovary. Credit: Science...
by Leigh Beeson, University of Georgia Credit: Journal of Medicinal Chemistry (2023). DOI: 10.1021/acs.jmedchem.3c00545 You’ve seen the commercial. The one that ominously tells you if you had chickenpox as a child, the virus that causes shingles is already inside you. It’s creepy, but it’s also a good way to prompt people to get the shingles vaccine. Unfortunately, the...
