by Shinshu University Patient with Parkinsonian gait disturbances seeking brain stimulation to improve walking dynamics. A sinusoidal waveform was utilized to delivery electrical current on the cerebellum. The initiation of each current coincided with the moment of heel contact on the affected side during a self-paced four minutes gait. Credit: Ippei Nojima Gait-related disturbances adversely...
This plant may be a surprise hero in our fight against fungal pathogens
By Bronwyn Thompson August 08, 2023 More than just a water feature: Scientists enlist plants to fight pathogens Depositphotos While water lilies are perhaps most famous for starring in French impressionist artist Claude Monet’s work, they may also have a molecular secret weapon that could help in our ongoing fight against fungal infections. After viruses...
Novel tool could help neuroscientists crack the secrets of spinal cord
Reviewed by Lily Ramsey, LLM Aug 7 2023 The spinal cord is harder to access and study than even the brain. The challenges posed by its mobility and anatomical structure have made understanding exactly how it functions difficult. Rice University engineers will work with collaborators to optimize an array of nanoelectronic threads, or NETs ⎯...
Weight Loss Drug Cuts Risk of Heart Problems, Maker Says
A clinical trial was the first to demonstrate that a new obesity drug could also improve patients’ heart health. By Benjamin Mueller Aug. 8, 2023 Updated 10:11 a.m. ET A new obesity drug, Wegovy, slashed the risk of serious heart problems by 20 percent in a large trial, the drug’s maker said on Tuesday, a...
Nanoscale ‘tattoos’ for individual cells could provide early warnings for health problems
by Johns Hopkins University False-colored gold nanodot array on a fibroblast cell. Credit: Kam Sang Kwok and Soo Jin Choi, Gracias Lab/Johns Hopkins University. Engineers have developed nanoscale tattoos—dots and wires that adhere to live cells—in a breakthrough that puts researchers one step closer to tracking the health of individual cells. The new technology allows for the first...
New Artificial Intelligence Program Could Help Treat Hypertension
Artificial intelligence model helps match people with high blood pressure to the medication most likely to work. For the nearly half of Americans with hypertension, it’s a potential death sentence; it increases the risk of stroke and chronic heart failure. While it’s relatively easy to prevent or moderate if caught early — eat well, exercise more,...
Wearable Device to Prevent Dangerous Dehydration
An innovative wearable device to warn of dehydration in the elderly is being designed by a University of Southampton researcher. The device could prevent serious illness and save lives every year – particularly when heatwaves hit. The device, which is under development, can be adapted and worn on different parts of the body (for example...
RNA-based Drug Delivered by Nanoparticles Destroys Most Cancer Cells in Bone Marrow
Using an RNA-based drug delivered to multiple myeloma blood cancer cells by targeted lipid nanoparticles, researchers at Tel Aviv University (TAU) destroyed 90% of the cells under laboratory conditions and 60% of the cells in human tissues. The researchers developed lipid-based nanoparticles, similar to those used in the COVID-19 vaccine, containing RNA molecules that silence the gene...
Biomaterial Injection Combines T Cell and Cancer Vaccine Treatments
AUGUST 7TH, 2023 CONN HASTINGS MATERIALS, MEDICINE, ONCOLOGY Researchers at the Harvard Wyss Institute have developed an anti-cancer biomaterial treatment that combines adoptive T cell therapy and cancer vaccine technology to treat solid tumors. The researchers have called their technique SIVET, which is short for “synergistic in situ vaccination enhanced T cell”. The approach combines local delivery of cytotoxic...
Human antibody that targets carfentanil, fentanyl and related opioids reverses overdose effects in preclinical study
SCRIPPS RESEARCH INSTITUTE IMAGE: A CRYSTAL STRUCTURE OF THE OPTIMIZED ANTIBODY, C10-S66K. THE BINDING POCKET OF C10‐S66K WITH FENTANYL AND CARFENTANIL IS DISPLAYED AS A GREY SURFACE WITH FENTANYL AND CARFENTANIL SHOWN AS GREEN AND YELLOW STICKS, RESPECTIVELY. CREDIT: SCRIPPS RESEARCH LA JOLLA, CA—An antibody in single-chain fragment variable (scFv) format that binds to the powerful opioid carfentanil...