Month: <span>August 2023</span>

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Intervention that leverages technology reduces depression in Indianapolis-area patients
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Intervention that leverages technology reduces depression in Indianapolis-area patients

by Indiana University–Purdue University Indianapolis School of Science Danielle Grounds, clinical research vascular sonographer in the IU School of Medicine, obtains ultrasound images for the measurement of brachial flow-mediated dilation, a barometer of cardiovascular disease risk. Credit: Indiana University–Purdue University Indianapolis School of Science The rapid expansion and normalization of e-health and telehealth brought about by the...

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Debate: Initial Combination Therapy for Type 2 Diabetes?

Miriam E. Tucker July 13, 2023 Should pharmacologic treatment of type 2 diabetes start with combination therapy or metformin monotherapy, adding other agents over time? This question was debated at the recent American Diabetes Association 83rd Scientific Sessions by two well-known clinician-researchers in the diabetes world. Ralph A. DeFronzo, MD, argued for combination therapy at the time of diagnosis,...

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Oral GLP-1 Agonists Could Be Game Changers for Obesity

Kevin Fernando, MBChB, MSc July 05, 2023 The advent of subcutaneously injectable GLP-1 receptor agonists for the management of type 2 diabetes during 2005 was arguably one of the greatest therapeutic advances for the condition since metformin. I was an early advocate of the class, given its potent glucose-lowering efficacy, secondary benefits of significant weight reduction, and...

How might obstructive sleep apnea heighten cardiovascular risk?
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How might obstructive sleep apnea heighten cardiovascular risk?

Lower blood oxygen levels due to sleep apnea may explain the higher cardiovascular risk faced by people with this condition. Image credit: milorad kravic/Getty Images. A new study finds that reduced blood oxygen levels may be a leading factor behind the link between obstructive sleep apnea and increased cardiovascular risk. Researchers reviewed data from more...

Rheumatoid arthritis tied to higher risk for aortic stenosis
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Rheumatoid arthritis tied to higher risk for aortic stenosis

by Lori Solomon Rheumatoid arthritis (RA) is associated with a higher risk for developing aortic stenosis, according to a study published online July 31 in JAMA Internal Medicine. Tate M. Johnson, M.D., from the VA Nebraska-Western Iowa Health Care System in Omaha, and colleagues examined the risk for incident aortic stenosis, aortic valve intervention, aortic stenosis-related death,...

Tracking periodontal disease to improve diagnosis and treatment
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Tracking periodontal disease to improve diagnosis and treatment

by Regenstrief Institute Developing automated computer algorithms to generate three patient cohorts. Credit: Diagnostics (2023). DOI: 10.3390/diagnostics13061028 Periodontal disease is a growing public health issue in the United States as the nation’s population ages, yet it’s underdiagnosed and undertreated. According to the U.S. Centers for Disease Control and Prevention (CDC), 47% of adults aged 30 years and older...

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At-Home Hormone Tests: Are They Accurate?

Ashley Lyles June 16, 2023 EDITORIAL COLLABORATIN MEDSCAPE& A proliferation of at-home tests are available to check thyroid function, and other hormones, offering patients the comfort of testing these levels remotely. This availability is expected to grow to a $4.79 billion market by 2030, according to Research and Markets analysis. The growing demand can be attributed partly to a...

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Lipid-lowering Therapies Should Be Guided by Vascular Imaging Rather Than by Circulating Biomarkers

Lale Tokgozoglu; David A. Morrow; Stephen J. Nicholls Eur Heart J. 2023;44(25):2292-2304.  Advantages of tailoring lipid lowering therapy with biomarkers versus imaging. Dyslipidemia is an important modifiable risk factor for atherosclerotic cardiovascular disease (ASCVD) and lipid lowering an integral component of cardiovascular prevention. Apolipoprotein B containing lipoproteins—mainly low-density lipoprotein cholesterol (LDL-C)—have indubitably been shown to be...