UNIVERSITY OF GOTHENBURG IMAGE: FREDRIK BÄCKHED AND MUHAMMAD TANWEER KHAN, SAHLGRENSKA ACADEMY AT THE UNIVERSITY OF GOTHENBURG. CREDIT: PHOTO: JOHAN WINGBORG, MUHAMMAD HUNAIN KHAN One of the beneficial gut bacteria residing in the human gut, which normally cannot survive in an environment with oxygen, can now be made oxygen-tolerant. This is a key finding in...
by Brown University Credit: CC0 Public Domain While mRNA vaccines against COVID-19 have been found to be safe and effective for the general population, in-depth evidence about safety and effectiveness for older adults and individuals with chronic health conditions is more limited. To address that gap, a team led by Brown University researchers conducted the largest...
by Brigham and Women’s Hospital Multiplexed immunofluorescence of synovial tissue. Multiplexed immunofluorescence images showing an example of a Ki67+PD-1+ synovial CD8 T cell (white arrow). CD3 staining is shown in red, CD8 in yellow, nuclear stain DAPI in blue, Ki67 in green and PD-1 in cyan. Credit: Science Immunology (2023). DOI: 10.1126/sciimmunol.add1591 Immune checkpoint inhibitor (ICI) therapies used to...
by Leslie Cantu, Medical University of South Carolina Graphical abstract. Credit: Journal of Clinical Investigation (2023). DOI: 10.1172/JCI168575 For someone with a blood cancer, receiving stem cells from a donor offers the possibility of a cure. But patients undergoing this procedure, called allogeneic hematopoietic cell transplantation, also face the possibility of a common side effect—graft-versus-host-disease (GVHD). In GVHD,...
by Laurel Hamers, University of Oregon Different affibodies (blue and orange) binding to BMP-2 (gray) in different locations. Credit: University of Oregon Instead of bulky metal plates and screws, bone fractures might someday be healed via targeted, controlled delivery of a specialized bone-growth protein. University of Oregon researchers have developed a system to get that protein to the...
by Osaka University Credit: European Journal of Heart Failure (2023). DOI: 10.1002/ejhf.2925 They say that an ounce of prevention is worth a pound of cure; knowing which preventive treatment to administer to which patient could undoubtedly up that yield. Now, an international research team led by Osaka University has identified an important treatment target that could help prevent patients from...
by University of California, Irvine Flow chart for subject participation. Bold font denotes subgroups that were included in the statistical analyses (Pre-Covid Finishers, for neuropsychological assessments; and MRI Finishers, for MRI analyses). Credit: Frontiers in Neuroscience (2023). DOI: 10.3389/fnins.2023.1200448 When a fragrance wafted through the bedrooms of older adults for two hours every night for six months, memories...
by Skolkovo Institute of Science and Technology Deuterium uptake in different organs of mice for various classes of lipids. Credit: International Journal of Molecular Sciences Scientists from Skoltech Institute of Science and Technology have proven that along with the level of biochemical substances in the living organism, we can also measure the substances’ turnover rate. This...
by West China Hospital of Sichuan University Tppp3+ tendon sheath progenitors expand at the heterotopic ossification (HO) induction site after Achilles tendon injury. a Schematic representation of HO induction, including complete Achilles tenotomy (left) and dorsal burn (right). b Tppp3ECE/+;R26RtdT animals wereadministered tamoxifen (TMx) for three continuous days, followed by a 10-day washout period before...
by James Cook University Impact of experimental hookworm infection on body mass. Credit: Nature Communications (2023). DOI: 10.1038/s41467-023-40263-4 A world-first human trial at James Cook University using live hookworms to combat diseases such as type 2 diabetes has proven successful—sparking interest in staging a larger-scale international trial. Dr. Doris Pierce from JCU’s Australian Institute of Tropical Health and...
