by Josh Barney, University of Virginia UVA researchers say they have found a biological process that contributes to the disease and may be a target for life-saving therapies. Credit: Emily Faith Morgan, University Communications University of Virginia Health researchers probing the causes of coronary artery disease have identified critical biological processes that can go wrong inside the linings of blood...
New Tool Provides Greater Accuracy for Medical Biosensors
University of Missouri researchers develop an innovative method using nanopores to help scientists advance their discoveries in neuroscience, other medical applications involving biosensors. For more than 20 years, Li-Qun “Andrew” Gu at the University of Missouri has developed a passion for solving life science problems by creating sophisticated diagnostic tools — on the nanoscale. Recently, Gu, a...
Pills From The 3D Printer
Pills could soon be produced in shapes that resemble design objects. And this would not be just an aesthetic gimmick, but would serve to release active medical ingredients in the body in a controlled manner. A group of computer scientists from the Max Planck Institute for Informatics in Saarbrücken and the University of California at...
New directions in microbiomes
FIRST HOSPITAL OF JILIN UNIVERSITY The field of gastroenterology and hepatology is experiencing a tremendous explosion of scientific knowledge and translational advances. It is a privilege to work in this field and to nurture the next generation of researchers and clinicians who will answer many critical questions and lessen the burden of digestive disease globally. Gastroenterology and...
Study shows promise of gene therapy for alcohol use disorder
OREGON HEALTH & SCIENCE UNIVERSITY A form of gene therapy currently used to treat Parkinson’s disease may dramatically reduce alcohol use among chronic heavy drinkers, researchers at Oregon Health & Science University and institutions across the country have found. The study in nonhuman primates showed that implanting a specific type of molecule that induces cell growth effectively...
New maps reveal the individual brain changes linked to different mental illness
MONASH UNIVERSITY A breakthrough project mapping brain changes in nearly 1,300 people diagnosed with six different types of mental illness has revealed the extraordinary diversity of brain changes found in people with conditions like major depression and schizophrenia. The study, published in Nature Neuroscience and led by researchers at Monash University’s Turner Institute for Brain and Mental Health and...
Stem-cell derived organoids secrete tooth enamel proteins
UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE/UW MEDICINE IMAGE: IN THIS LAB IMAGE OF A DEVELOPING INCISOR TOOTH, COLORS IDENTIFY WHICH GENES ARE BEING EXPRESSED AT EACH STAGE OF DEVELOPMENT. CREDIT: UNIVERSITY OF WASHINGTON DENTAL ORGANOID RESEARCH GROUP Organoids have now been created from stem cells to secrete the proteins that form dental enamel, the substance that protects...
Simple noninvasive test may lead to breakthrough in early diagnosis of bladder cancer
ELSEVIER IMAGE: FRESH VOIDED URINE SAMPLES WERE COLLECTED INTO TUBES CONTAINING PRESERVATIVE BUFFER. TOTAL DNA WAS EXTRACTED FROM THE URINE SEDIMENTS AND UNDERWENT BISULFITE CONVERSION. SUBSEQUENTLY, LINEAR TARGET ENRICHMENT (LTE) AND QUANTITATIVE METHYLATION-SPECIFIC PCR (QMSP) WERE CONDUCTED TO DETERMINE THE LEVEL OF PENK METHYLATION ASSOCIATED WITH BLADDER CANCER. A POSITIVE RESULT INDICATES A HIGHER PROBABILITY...
Genetically engineered bacteria can detect cancer cells in a world-first experiment
by Dan Worthley, The Conversation Credit: Shutterstock As medical technology advances, many diseases could be detected, prevented and cured with cells, rather than pills. This branch of medicine is called cellular or cell therapy. It’s already used in clinical practice in some situations, such as patients receiving fecal microbial transplants (“poo transplants”) when they have a severe gastrointestinal infection,...
Source of hidden consciousness in ‘comatose’ brain injury patients found
by Columbia University Irving Medical Center Hidden consciousness researchers Qi Shen, left, Angela Velasquez, center, and Jan Claassen. Credit: Rudy Diaz / Columbia University Irving Medical Center Columbia researchers have identified brain injuries that may underlie hidden consciousness, a puzzling phenomenon in which brain-injured patients are unable to respond to simple commands, making them appear unconscious despite having some level...