by King’s College London Credit: CC0 Public DomainResearchers have revealed a new mechanism of targeted drug treatment used against chronic lymphocytic leukemia, through the promotion of immune cell function, that could be exploited using new anti-cancer immunotherapies. New research has revealed how a class of new medicines used to treat the blood cancer chronic lymphocytic leukemia...
Research shows new documentation tool could help optimize seizure treatments in patients with epilepsy
by CU Anschutz Medical Campus Credit: Pixabay/CC0 Public DomainNew research from the University of Colorado Anschutz Medical Campus studies a new tool that will help medical providers identify patients who are failing epilepsy treatments earlier in order to change treatment to rapidly optimize positive outcomes. The study was published online today in Neurology Clinical Practice. The...
‘I’d rather not know’: Why we choose ignorance
by American Psychological Association Credit: Pixabay/CC0 Public DomainWhen given the choice to learn how their actions will affect someone else, 40% of people will choose ignorance, often in order to have an excuse to act selfishly, according to recent research. “Examples of such willful ignorance abound in everyday life, such as when consumers ignore information about...
Scientists Spot Genes Linked to Raynaud’s Phenomenon
(Adobe Stock) Scientists have discovered two genes that may trigger Raynaud’s phenomenon, a condition that can cause fingers and toes to go cold and numb because of the constriction of tiny blood vessels under the skin. “We identify two distinct genes that point to two distinct mechanisms,” lead researcher Maik Pietzner, chair in health data...
Scientists Find the ‘On’ Switch for Energy-Burning Brown Fat
Courtney Southwick October 17, 2023 A process your body uses to stay warm in cool weather could one day lead to new therapies for obesity. Scientists have, for the first time, mapped the precise nerve pathways that activate brown fat, or brown adipose tissue (BAT), a specialized fat that generates heat. Low temperatures kick brown fat into...
Study highlights the key role of the prefrontal cortex in regulating REM sleep
by Ingrid Fadelli , Medical Xpress Optogenetic activation of mPFC Pyr neurons triggers REM sleep. a, Top: schematic of optogenetic activation of mPFC Pyr neurons. Bottom: expression of AAV-CaMKII-ChR2-eYFP (yellow) in mPFC of a C57BL/6J mouse. Dashed lines, optic fiber tract. Scale bar, 500 µm. Brain atlas image adapted with permission from ref. 61. b, Example...
Novel hydrogel finds new aptamers, or ‘chemical antibodies,’ in days
by Tim Schley, Pennsylvania State University A new method for selecting aptamers, or ‘chemical antibodies,’ created by Penn State engineers takes only days to complete, instead of the months typically needed for traditional methods. Credit: Kate Myers/Penn StateOne double-helix strand of DNA could extend six feet, but it is so tightly coiled that it packs an...
I’m not going to be cured’. How breast cancer awareness and support sidelines people with metastatic disease
by Sophie Lewis, Andrea Smith and Katherine Kenny, The Conversation Credit: ShutterstockThere have been incredible advances in breast cancer diagnosis and treatment in recent years. And stories about celebrities who have “beaten” breast cancer continue to be a source of inspiration for many people. However, this emphasis on fighting, beating and surviving cancer shuts out...
Research discovers the morning-after pill is more effective when taken with an anti-inflammatory painkiller
by The University of Hong Kong Study shows that the percentage of pregnancies prevented by piroxicam-levonorgestrel co-treatment was significantly higher than that of the levonorgestrel emergency contraceptive pill alone. Credit: The Lancet (2023). DOI: 10.1016/S0140-6736(23)01240-0A collaborative research team, including members of LKS Faculty of Medicine of the University of Hong Kong (HKUMed), as well as The...
Researchers design gene therapy that can effectively target glioblastoma
by Brigham and Women’s Hospital Glioblastoma (histology slide). Credit: Wikipedia/CC BY-SA 3.0Glioblastoma (GBM), an aggressive brain cancer, is notoriously resistant to treatment, with recurrent GBM associated with survival of less than 10 months. Immunotherapies, which mobilize the body’s immune defenses against a cancer, have not been effective for GBM, in part because the tumor’s surrounding environment...