By Pooja Toshniwal PahariaOct 30 2023Reviewed by Susha Cheriyedath, M.Sc. In a recent study published in the journal Nutrients, researchers performed a meta-analysis to determine the association between fish consumption and cardiovascular disease (CVD) risk.The Importance of Diet in Cardiovascular Health Studies show that unhealthy dietary habits and sedentary lifestyles contribute to the high mortality...
FDA warns eyedrops from major brands may cause infection
by Cara Murez Federal regulators are warning consumers to stop using eyedrops and gels from several major brands after finding unsanitary conditions in a manufacturing plant. Twenty-six eye care products are part of the alert. Contaminated products have the potential to cause eye infection and blindness because drugs applied to the eye can bypass some...
FDA approves mirikizumab, a promising induction and maintenance therapy for ulcerative colitis
by The Mount Sinai Hospital Endoscopic image of a bowel section known as the sigmoid colon afflicted with ulcerative colitis. The internal surface of the colon is blotchy and broken in places. Credit: Samir/Wikipedia The U.S. Food and Drug Administration (FDA) approved mirikizumab, on October 26, 2023, a highly effective new treatment for ulcerative colitis (UC),...
Weekly insulin injections could be as effective in diabetes management as daily injection regimes
by University of Surrey Credit: Artem Podrez from Pexels Insulin icodec, a once-weekly basal injection to treat type 1 diabetes, has the potential to be as effective in managing the condition as daily basal insulin treatments, according to research from the University of Surrey. The results of the year-long phase 3 clinical trial could revolutionize the...
Study links specific gut bacteria to increased risk of severe malaria
by Indiana University Shotgun metagenomics revealed distinct gut microbiota composition and genetic potential within and between the hyperparasitemia resistant and susceptible mice. a C57BL/6 mice were acquired from four different vendors (N = 15/group): Charles River Laboratories (CR), Envigo (Env), Taconic Biosciences (Tac), and Jackson Laboratory (Jax). Mice from Taconic Biosciences were obtained from two different facilities with...
Improving deep sleep may prevent dementia, study finds
by Monash University Credit: Pixabay/CC0 Public Domain As little as 1% reduction in deep sleep per year for people over 60 years of age translates into a 27% increased risk of dementia, according to a study which suggests that enhancing or maintaining deep sleep, also known as slow wave sleep, in older years could stave off...
Protein eIF4A emerges as a potential Achilles’ heel for triple-negative breast cancer
by Baylor College of Medicine Graphical abstract. Credit: Journal of Clinical Investigation (2023). DOI: 10.1172/JCI172503 Improving treatments for triple-negative breast cancer (TNBC), an aggressive tumor with very poor prognosis and limited therapeutic targets, has been challenging. Responding to this need for better treatments, researchers at Baylor College of Medicine and collaborating institutions have investigated potential vulnerabilities...
Protein interaction causing rare but deadly vaccine-related clotting found
by University of Birmingham PF4 binding to c-Mpl disrupts TPO binding. (A) AlphaFold prediction of the binding of PF4 and TPO to c-Mpl. Overlayed cartoon structures of c-Mpl (green) complexed with either PF4 (blue) or TPO (orange) as modeled using Colabfold. Structure predictions were ranked by pLDDT, a per-residue measure of the confidence of the predicted...
Common chemotherapy drugs don’t work like doctors thought, with big implications for drug discovery
by Will Cushman, University of Wisconsin-Madison A cancer cell undergoing abnormal mitosis and dividing into three new cells rather than two following treatment with a microtubule poison. Credit: Beth Weaver, University of Wisconsin–Madison A new study from the University of Wisconsin–Madison suggests that chemotherapy may not be reaching its full potential, in part because researchers and...
How to lower uric acid levels naturally and manage gout
Dietary measures, medications, and supplements can all help reduce uric acid and manage gout. Gout can occur when blood uric acid levels are too high, causing crystals to form in the feet, toes, and other joints. Uric acid is a chemical the body creates when it breaks down purines. The body creates purines, and some...