Month: <span>November 2023</span>

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How Cell Identity is Preserved when Cells Divide

Posted Today MIT study suggests 3D folding of the genome is key to cells’ ability to store and pass on “memories” of which genes they should express. HeLa cells stained for nuclear DNA with the blue fluorescent Hoechst dye. On the left, a cell is going through mitosis and its DNA has condensed. Every cell in...

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DRUG DISCOVERY PAVES WAY FOR PANCREATIC CANCER CLINICAL TRIAL

NOVEMBER 17TH, 2023POSTED BY LESLIE ORR-ROCHESTER In mice and in tissue studies, when researchers suppressed Netrin-1 with the anti-cancer drug (NP137), cancer was less likely to spread and cancer cell death occurred. (Credit: Getty Images) Laboratory findings have set the stage for a clinical trial investigating a drug for pancreatic cancer that has spread to the liver....

Nanoplastics Promote Conditions for Parkinson’s Across Various Lab Models
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Nanoplastics Promote Conditions for Parkinson’s Across Various Lab Models

DURHAM, N.C. – Nanoplastics interact with a particular protein that is naturally found in the brain, creating changes linked to Parkinson’s disease and some types of dementia. In a Duke-led study appearing Nov. 17 in Science Advances, the researchers report that the findings create a foundation for a new area of investigation, fueled by the...

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Liver cancer rates increase in each successive generation of Mexican Americans, study finds

The research, led by the Keck School of Medicine of USC, analyzed risk for the disease across more than 30,000 Mexican Americans, finding third-generation Mexican Americans 66% more likely to get liver cancer than the first generation.Peer-Reviewed Publication KECK SCHOOL OF MEDICINE OF USC In the United States, liver cancer rates have more than tripled...

Our cerebellar nuclei turn out to be more important than initially thought
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Our cerebellar nuclei turn out to be more important than initially thought

Peer-Reviewed Publication CHAMPALIMAUD CENTRE FOR THE UNKNOWN AN ARTISTIC INTERPRETATION OF THE RESEARCH. THE BRIGHT ALGAE REPRESENT MOSSY FIBERS — BRAIN CONNECTIONS THAT INTERACT WITH PUFFERFISH, SYMBOLIZING THE CEREBELLAR NUCLEI CELLS THAT RESPOND VARIABLY TO STIMULI. THE BOAT’S TIMBER PATTERNS ABOVE SUGGEST THE STRUCTURE OF THE CEREBELLAR CORTEX, LINKED TO THE DEPTHS BY AN ANCHOR...

Research reveals alarming rates of suicidal ideation among older transgender adults
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Research reveals alarming rates of suicidal ideation among older transgender adults

by Taylor & Francis Credit: Pixabay/CC0 Public Domain Transgender adults aged 50 or older in the United States face a significantly elevated risk of contemplating suicide due to the compounding impact of various challenges in different areas of their lives, according to a population-wide study. More than one-fourth (25.8%) of this large pool of older transgender...

Hidden belly fat in midlife linked to Alzheimer’s disease
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Hidden belly fat in midlife linked to Alzheimer’s disease

by Radiological Society of North America Increased neuroinflammation (yellow colors) associated with higher hidden fat (visceral fat) in the cohort of 54 participants with an average age of 50 years in the brain’s white matter. The green colors are the normal white matter. Credit: RSNA/Mahsa Dolatshahi, M.D., M.P.H. Higher amounts of visceral abdominal fat in midlife...

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How Targeted Drugs Can Vanquish a Virulent Leukemia

Randy Dotinga For patients with acute myeloid leukemia (AML), especially those who are older or have relapsed/refractory disease, standard chemotherapy treatments often fail to change their poor clinical trajectories. These days, however, a new era of targeted therapy is improving prognoses somewhat — and raising hopes that even bigger advancements are on the horizon. “We...