Year: <span>2023</span>

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New computer program ‘learns’ to identify mosaic mutations that cause disease
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New computer program ‘learns’ to identify mosaic mutations that cause disease

by University of California – San Diego This image was generated by artificial intelligence based upon a request for 3D art using a natural language interpretation of “artificial intelligence that detects mutations in the genome.” Credit: Joseph Gleeson/UC San Diego Genetic mutations cause hundreds of unsolved and untreatable disorders. Among them, DNA mutations in a...

High-tech tiny ‘plug’ to soothe dry eyes could offer an alternative for patients who struggle with drops
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High-tech tiny ‘plug’ to soothe dry eyes could offer an alternative for patients who struggle with drops

By ROGER DOBSON FOR THE DAILY MAIL PUBLISHED: 20:10 EST, 2 January 2023 | UPDATED: 20:12 EST, 2 January 2023 A tiny plug placed in a tear duct could mean the end of daily drops for patients with dry eyes. The high-tech plug — the size of a grain of rice — continuously releases anti-inflammatory medication for three months. It’s...

Your microbiome ages as you do—and that’s a problem
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Your microbiome ages as you do—and that’s a problem

KATERYNA KON/SCIENCE PHOTO LIBRARY VIA GETTY This article is from The Checkup, MIT Technology Review’s weekly biotech newsletter. We’re all crawling with bugs. Our bodies are home to plenty of distinct ecosystems that are home to microbes, fungi, and other organisms. They are crucial to our well-being. Shifts in the microbiome have been linked to...

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KAIST’s neuroscientist announces recent advancements toward finding a cure for dystonia

Reviewed by Emily Henderson, B.Sc. Jan 1 2023 KAIST’s neuroscientist and professor, Dr. Daesoo Kim attended the “Conference for Musicians with Dystonia” supported by the World Health Organization (WHO) and the Carnegie Hall concert of legendary pianist João Carlos Martins, who is also a dystonia patient, to announce his team’s recent advancements toward finding a...

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Duping antibodies with a decoy, researchers aim to prevent rejection of transplanted cells

UNIVERSITY OF CALIFORNIA – SAN FRANCISCO Duping Antibodies with a Decoy, Researchers Aim to Prevent Rejection of Transplanted Cells New Approach May Overcome Persistent Obstacles to Cell Transplantation and Immunotherapy  Researchers at UCSF have developed a novel, potentially life-saving approach that may prevent antibodies from triggering immune rejection of engineered therapeutic and transplant cells.  Rejection mediated by antibodies—as opposed...

New method precisely locates gene activity and proteins across tissues
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New method precisely locates gene activity and proteins across tissues

WEILL CORNELL MEDICINE IMAGE: IMAGE OF HUMAN BREAST CANCER CELLS SHOWING A) IMMUNOSUPPRESSIVE MACROPHAGES NEAR TUMOR CONNECTIVE TISSUE, AND B) IMMUNOSTIMULATORY MACROPHAGES NEAR TUMOR NESTS. CREDIT: NIR BEN CHETRIT. A new method can illuminate the identities and activities of cells throughout an organ or a tumor at unprecedented resolution, according to a study co-led by researchers at...

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Self-assembling proteins can store cellular “memories”

MASSACHUSETTS INSTITUTE OF TECHNOLOGY CAMBRIDGE, MA — As cells perform their everyday functions, they turn on a variety of genes and cellular pathways. MIT engineers have now coaxed cells to inscribe the history of these events in a long protein chain that can be imaged using a light microscope. Cells programmed to produce these chains...

New Research: Intermittent Fasting Might Not Be As Safe as We Thought
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New Research: Intermittent Fasting Might Not Be As Safe as We Thought

By UNIVERSITY OF TORONTO JANUARY 1, 2023 Intermittent fasting is a popular dietary trend that involves cycling between periods of eating and fasting. It is believed to have various health benefits such as weight loss, improved insulin sensitivity, and reduced inflammation. The popular dietary trend has been linked to dangerous eating disorder attitudes and behaviors among adolescents...

A Single Hormone in Men May Predict Their Future Health
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A Single Hormone in Men May Predict Their Future Health

02 January 2023 By DAVID NIELD (Fizkes/iStock/Getty Images Plus) A variety of age-related illnesses – including bone weakness, sexual dysfunction, diabetes, cancer, and cardiovascular disease – can be predicted by a single hormone that appears at a steady level in men across the course of their lives, new research reveals. That hormone is INSL3, and it first appears during puberty....

Revised clinical trial form for Alzheimer’s antibody warned of fatal brain bleeds
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Revised clinical trial form for Alzheimer’s antibody warned of fatal brain bleeds

30 DEC 2022 11:30 AM BY CHARLES PILLER Alzheimer’s patients with cerebral amyloid angiopathy—a condition in which beta amyloid deposits (red) replace the smooth muscle of blood vessels (green)—are particularly vulnerable to brain bleeds when taking lecanemab concurrently with blood thinners. LISSA VENTURA-ANTUNES Earlier this year, the developer of a promising antibody designed to slow...