Year: <span>2023</span>

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Tissue-specific immunity may be the future, if we can first learn its rules
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Tissue-specific immunity may be the future, if we can first learn its rules

by University of California – San Diego T cells play an important role in immunity, autoimmunity and cancer. Credit: National Institute of Allergy and Infectious Diseases, National Institutes of Health Recent pressure to maximize vaccine efficacy has stirred up many new discoveries within immunology, revealing numerous paradigms with untapped therapeutic potential. One growing branch of research is...

Alveolar macrophages help CD8+ T cells go (anti-)viral
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Alveolar macrophages help CD8+ T cells go (anti-)viral

NARA INSTITUTE OF SCIENCE AND TECHNOLOGY IMAGE: INFLUENZA VIRUS-SPECIFIC CD8+ T CELLS INDUCED IN LYMPH NODES AS A RESULT OF INFLUENZA VIRUS INFECTION OR VACCINATION CIRCULATE THROUGHOUT THE BODY. DURING SECOND INFLUENZA VIRUS INFECTION, VIRAL FRAGMENTS TAKEN UP BY ALVEOLAR MACROPHAGES (AMS) ARE PRESENTED AS ANTIGENS TO PROMOTE VIRUS-SPECIFIC CD8+ T CELLS PROLIFERATION. THE PROLIFERATED...

Actinidia arguta (sarunashi) juice inhibits lung cancer in mice
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Actinidia arguta (sarunashi) juice inhibits lung cancer in mice

OKAYAMA UNIVERSITY IMAGE: IN A STUDY BY RESEARCHERS FROM OKAYAMA UNIVERSITY, ACTINIDIA ARGUTA (SARUNASHI) JUICE REDUCED TUMOR NODULES IN CARCINOGEN-EXPOSED MICE CREDIT: SAKAE ARIMOTO‑KOBAYASHI Lung cancer is the leading cause of death in Japan and across the globe. Among all the cancers, lung cancer has one of the lowest five-year survival rates. Smoking tobacco and...

Some guts are better than others at harvesting energy, study shows
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Some guts are better than others at harvesting energy, study shows

by University of Copenhagen Enterotypes differ in stool energy density, intestinal transit time, microbial alpha-diversity, and body weight. a The study included baseline measurements of 85 overweight subjects. Prior to collection of the stool and urine samples used in the study, habitual dietary intake was estimated based on 4-day dietary registrations and intestinal transit time was estimated...

Wafer-thin device has potential to transform the field of islet cell transplantation
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Wafer-thin device has potential to transform the field of islet cell transplantation

by Houston Methodist The Neovascularized Implantable Cell Homing and Encapsulation (NICHE) device is about the size of a quarter. Credit: Houston Methodist A quarter-sized device created at Houston Methodist could drastically alter the course of treatment for type 1 diabetes, a chronic condition that impacts millions of Americans and does not have a cure. In...

Eye tracking during visual challenges reveals neural encoding
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Eye tracking during visual challenges reveals neural encoding

by Weizmann Institute of Science Credit: Weizmann Institute of Science “Seeing eye to eye” is an expression of harmony, but do different people literally see the same thing when they view the same external world? “The short answer is—no,” says Dr. Liron Gruber. “Even the same person sees the same thing differently each time they...

Immunologists uncover obesity-linked trigger to severe form of liver disease
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Immunologists uncover obesity-linked trigger to severe form of liver disease

by UT Southwestern Medical Center Graphical abstract. Credit: Immunity (2022). DOI: 10.1016/j.immuni.2022.11.013 UT Southwestern immunologists have uncovered a key pathogenic event prompted by obesity that can trigger severe forms of nonalcoholic fatty liver disease and potential liver failure. The finding, published in Immunity, could pave the way for developing therapies to treat nonalcoholic steatohepatitis (NASH). The team led...

Risk for persistent postural perceptual dizziness increases with vestibular conditions, study finds
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Risk for persistent postural perceptual dizziness increases with vestibular conditions, study finds

by Elana Gotkine HealthDay Reporter  Patients with multiple vestibular conditions have an increased risk for persistent postural perceptual dizziness (PPPD), according to study published online Oct. 27 in Audiology Research. Valeria Gambacorta, M.D., from the University of Perugia in Italy, and colleagues analyzed the role of benign paroxysmal positional vertigo (BPPV), vestibular migraine (VM), and Ménière disease...

Brain area necessary for fluid intelligence identified
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Brain area necessary for fluid intelligence identified

by University College London Credit: Pixabay/CC0 Public Domain A team led by UCL and UCLH researchers have mapped the parts of the brain that support our ability to solve problems without prior experience—otherwise known as fluid intelligence. Fluid intelligence is arguably the defining feature of human cognition. It predicts educational and professional success, social mobility, health, and...

New biomarker test can detect Alzheimer’s neurodegeneration in blood
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New biomarker test can detect Alzheimer’s neurodegeneration in blood

by University of Pittsburgh Credit: Pixabay/CC0 Public Domain A group of neuroscientists led by a University of Pittsburgh School of Medicine researcher developed a test to detect a novel marker of Alzheimer’s disease neurodegeneration in a blood sample. A study on their results was published today in Brain. The biomarker, called brain-derived tau, or BD-tau, outperforms...