by Cleveland Clinic Credit: Unsplash/CC0 Public DomainCleveland Clinic researchers have identified a new pathway that contributes to cardiovascular disease associated with high levels of niacin, a common B vitamin previously recommended to lower cholesterol. The team, led by Stanley Hazen, M.D., Ph.D., discovered a link between 4PY, a breakdown product from excess niacin, and heart disease....
by Hannah Furfaro, The Seattle Times Credit: CC0 Public DomainAndrea Boyd’s son has been in crisis often enough to know the urgency of getting treatment when he needs it. In his 20s, without proper care and medication, he drifted onto the streets for nearly a decade. He also knows the specific kind of care he...
by Dennis Thompson When settling into your senior years, you need to be especially careful when taking medicines, herbal remedies and supplements, the U.S. Food and Drug Administration says. That’s because older adults are likely to use more prescription and over-the-counter medications, which increases the risk of harmful side effects and drug interactions, the FDA...
Lucy Hicks It’s no secret that regular exercise is important. But for patients with painful joints, it can be the last thing they want to do. Exercise is one of the cornerstones of managing arthritis, yet nearly one third of patients with arthritis are inactive. Guidelines recommend that clinicians encourage their patients to engage in...
Gwendolyn Rak Neurologic damage following acute viral infections may be attributed to an excessive immune response to the infection, according to a new study.Many viral infections that don’t directly infect the central nervous system (CNS) have been associated with severe neurologic disease. For these viruses, including newer viruses such as SARS-CoV-2 and Zika, the mechanism...
by Ghent University Longitudinal images of an affected joint. Credit: Nature Medicine, DOI: 10.1038/s41591-024-02822-0Researchers at Ghent University Hospital, Ghent University, and VIB-UGent Center for Inflammation Research, show that antibody therapy can be effective against erosive hand osteoarthritis. Using the antibody denosumab leads to bone remodeling and the prevention of erosive joint damage. This is the first...
by University of Birmingham AML-subtype specific gene expression and chromatin accessibility is established in LSCs. Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-45691-4The mystery of why myeloid leukemia starts to grow again after chemotherapy has killed the bulk of malignant cells, and how growth may be blocked by repurposed drugs, has potentially been solved through new research. The...
by Bob Yirka , Medical Xpress Helical mCR with articulated magnetic tip. (A) The helical protrusion on the outer surface of the continuum robot, upon rotation, pushes the robot tip forward. (B) The segmented articulating magnetic tip increases the magnetic volume and decreases bending stiffness for improved steerability. (C) The helical robot prevents buckling and...
by Elana Gotkine For patients with relapsing multiple sclerosis, the anti-CD40L monoclonal antibody frexalimab has a favorable effect on the number of new gadolinium-enhancing T1-weighted lesions, according to a study published in the Feb. 15 issue of the New England Journal of Medicine.Patrick Vermersch, M.D., Ph.D., from the University of Lille in France, and colleagues...
by British Medical Journal Credit: Unsplash/CC0 Public DomainWalking or jogging, yoga and strength training seems to be the most effective exercises to ease depression, either alone or alongside established treatments such as psychotherapy and drugs, suggests an evidence review published by The BMJ. Even low-intensity activities such as walking or yoga are beneficial, but the results...
