by Tessa Roy, University of Michigan Increased fibroblast synthetic activity as early as 1 week post-filler injection. Following injection of vehicle (saline) and filler (cross-linked hyaluronic acid, CL-HA) into photodamaged skin of individuals over 60 years-old, skin samples were obtained in a paired manner at 1, 2, 3 and 4 weeks. Credit: Experimental Dermatology (2024). DOI: 10.1111/exd.14998Chronic exposure of...
Month: <span>February 2024</span>
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Is surgery the best option for ruptured Achilles tendons in young adults?
by University of Michigan Credit: Pixabay/CC0 Public DomainAn Achilles tendon rupture typically means surgery for many patients. A research team led by Laurence Ge, M.D., an orthopedic surgery resident mentored by Paul Talusan, M.D. at University of Michigan Health, looked at the difference in outcomes of those treated with and without surgical procedures for their Achilles...
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Health and zombie cells in aging
Peer-Reviewed Publication MAYO CLINIC With age, cells can experience senescence, a state where they stop growing but continue releasing inflammatory and tissue-degrading molecules. When a person is young, the immune system responds and eliminates senescent cells, often referred to as zombie cells. However, zombie cells linger and contribute to various age-related health problems and diseases....
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The Prospect of a Medication to Treat OSA Is Getting Closer
Bertrand Herer, MD For researchers involved with sleep disorders, developing a pharmacologic treatment for obstructive sleep apnea (OSA) is a bit like searching for the holy grail. P K Schweitzer and colleagues have published the results of the randomized MARIPOSA study assessing a combination of two medicinal products known as AD109, one of the products...
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Measles infections pose far more risks than most realize, including a fatal neurological complication
Liz Szabo Erica Finkelstein-Parker planned her daughter’s 8th birthday party with love. Because Emmalee adored airplanes, Finkelstein-Parker chose the theme “Flying High with Emmalee.” Finkelstein-Parker filled nearly two dozen brightly colored goody bags for Emmalee’s friends — one for every child in her class, so no one would feel left out. Months later, the treat...
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New technique for revealing genetic repeats yields surprising insights into Huntington’s disease
by Rockefeller University Credit: Neuron (2024). DOI: 10.1016/j.neuron.2023.12.009Neurodegenerative diseases are among the most complex human ailments, and their exact causes and mechanisms are the subject of ongoing research and debate. When it comes to Huntington’s disease, steadily accumulating evidence over the past 30 years has led to a model of molecular events that explains several key...
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Pickleball-related fractures up significantly in older adults
by Lori Solomon As pickleball has gained in popularity, associated fractures have skyrocketed 90-fold since 2002, according to a study presented at the 2024 Annual Meeting of the American Academy of Orthopedic Surgeons, held from Feb. 12 to 16 in San Francisco. Yasmine S. Ghattas, from University of Central Florida in Orlando, and colleagues used...
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Antihypertensive combos recommended for BTKi-linked hypertension
by Elana Gotkine Specific combinations of antihypertensives are recommended for patients with Bruton’s tyrosine kinase inhibitor (BTKi)-associated hypertension (HTN), according to a study published online Feb. 5 in Blood Advances. Laura Samples, M.D., from the Fred Hutchinson Cancer Center in Seattle, and colleagues examined the optimal treatment of BTKi-associated HTN in a study involving randomly...
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Research finds brain cancer risk increase after moderate/severe, penetrating TBI
by Elana Gotkine Moderate/severe and penetrating traumatic brain injury (TBI) are associated with an increased risk for subsequent development of brain cancer, according to a study published online Feb. 15 in JAMA Network Open. Ian J. Stewart, M.D., from the Uniformed Services University of Health Sciences in Bethesda, Maryland, and colleagues conducted a retrospective cohort...
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FDA expands use of asthma med Xolair to treat food allergies
by Ernie Mundell People threatened by accidental exposure to foods they’re allergic to may have a new weapon of defense: On Feb. 16, the U.S. Food and Drug Administration expanded the use of the asthma drug Xolair to help prevent anaphylactic reactions. Xolair (omalizumab) is an injected drug and is not meant as a substitute...