A new study finds precancerous colon cells turn on a gene called SOX17, which helps them evade detection and develop into more advanced tumors.Peer-Reviewed Publication MASSACHUSETTS INSTITUTE OF TECHNOLOGY CAMBRIDGE, MA — One of the immune system’s primary roles is to detect and kill cells that have acquired cancerous mutations. However, some early-stage cancer cells...
Month: <span>February 2024</span>
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How 40Hz sensory gamma rhythm stimulation clears amyloid in Alzheimer’s mice
Stimulating a key brain rhythm with light and sound increases peptide release from interneurons, driving clearance of Alzheimer’s protein via the brain’s glymphatic system, new study suggestsPeer-Reviewed Publication PICOWER INSTITUTE AT MIT BRIGHT STAINING HIGHLIGHTS VIP-EXPRESSING INTERNEURONS IN THIS CORONAL CROSS-SECTION OF A MOUSE BRAIN. THE NEURONS MAY HELP DRIVE GLYMPHATIC CLEARANCE OF AMYLOID VIA...
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Calcium crystal deposits in the knee contribute to joint damage
Targeting calcium crystal deposits could help relieve painPeer-Reviewed Publication BOSTON UNIVERSITY SCHOOL OF MEDICINE (Boston)— Knee osteoarthritis (OA) is the most common form of arthritis, affecting approximately 600 million people worldwide and 34 million people in the U.S. There are no treatments available that prevent its progression to date. Recommended pharmacological treatments for symptoms have...
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Nanocarrier with escape reflex
Tumor-specific drug release through controlled endosomal escapePeer-Reviewed Publication WILEY Protein-based drugs must be transported into cells in a way that prevents their immediate degradation. A new approach is intended to ensure that they remain intact only in certain cells, such as cancer cells. In the journal Angewandte Chemie, a Japanese research team has introduced a...
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N₂O laughing matter: Self-adjusted nitrous oxide takes the pain out of prostate cancer screening procedure
by Beth Israel Deaconess Medical Center Graphical Abstract. Credit: Journal of Urology (2023). DOI: 10.1097/JU.0000000000003789Each year, more than a million transrectal biopsies are performed in the United States. The primary technique for diagnosing and monitoring prostate cancer, a transrectal biopsy, entails removing tissue from the prostate gland by inserting a thin needle through the rectal wall....
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Promising pathways to simplified Alzheimer’s diagnosis unveiled in groundbreaking study
The results of the Bio-Hermes study appear in Alzheimer’s & Dementia showing how new Alzheimer’s detecting blood tests perform across a broad range of races and ethnicities for the first timePeer-Reviewed Publication GLOBAL ALZHEIMER’S PLATFORM FOUNDATION GLOBAL ALZH CREDIT: GLOBAL ALZHEIMER’S PLATFORM FOUNDATION Washington D.C., Feb. 28, 2024- The Global Alzheimer’s Platform Foundation®, (GAP) is...
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Anti-ageing drug rapamycin improves immune function through endolysosomes
Protection against an increase in pro-inflammatory factors with agePeer-Reviewed Publication MAX PLANCK INSTITUTE FOR BIOLOGY OF AGEING RAPAMYCIN IS ONE OF THE MOST PROMISING ANTI-AGEING SUBSTANCES TO DATE. RAPAMYCIN IS NAMED AFTER “RAPA NUI”, THE LOCAL TRANSLATION FOR THE EASTER ISLANDS, WHERE THE ACTIVE INGREDIENT WAS DISCOVERED AS A METABOLIC PRODUCT OF BACTERIA IN A...
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Hypersensitive touch sensor ‘feels’ things from 4 inches away
By Paul McClure Sensors that can ‘feel’ without touching have potential uses across a number of fieldsAI-generated by DALL-E Using a 3D-printed material sensitive to electric fields, researchers have created a novel sensor that can accurately recognize and distinguish objects up to 10 centimeters – about four inches – away without needing to touch them physically....
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Resistant starch diet proves a game changer for weight loss and diabetes control
By Dr. Chinta SidharthanFeb 27 2024Reviewed by Susha Cheriyedath, M.Sc.In a recent study published in the journal Nature Metabolism, a team of scientists investigated whether modulation of the gut microbiome using dietary fiber supplementation in the form of resistant starch could help with insulin resistance and weight loss and offer a potential treatment avenue for...
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Molecular clusters on glial cells show they are more than our brain’s ‘glue’
by Fred Hutchinson Cancer Center Graphical abstract. Credit: Cell Reports (2024). DOI: 10.1016/j.celrep.2024.113844Neuroscientists at Fred Hutchinson Cancer Center have found that an often-overlooked type of brain cell called glia has more of a role in brain function than previously thought. In the journal Cell Reports, Fred Hutch neuroscientist Aakanksha Singhvi, Ph.D., and her team report that...