Aude Lecrubier Cases of menstrual disorders, particularly unusually heavy menstrual bleeding, have been reported following RNA vaccination against COVID-19. In France, this safety signal has been confirmed and added to the product characteristics summaries and vaccine leaflets for mRNA vaccines in October 2022. However, few studies have accurately measured this risk to date. To address...
Can an experimental cell phone app screen coughs for TB? Scientists say ‘yes’
by Delthia Ricks , Medical Xpress (A) Study protocol for the audio data collection at Kenya Medical Research Institute (KEMRI), Nairobi and subsequent cough annotation at the University of Washington, Seattle. (B) The bar graphs represent the total passive and voluntary coughs (including all recording devices) in the Nairobi cough dataset. The lighter shade in...
Researchers discover new cell that remembers allergies
by McMaster University Image depicting UMAP of mass cytometry data analyzing human B cell subsets. Credit: Depiction generated by David R. Glass, project lead by Joshua F.E. Koenig, Peter Sejer Andersen, Niels Peter H. Knudsen, Allyssa Phelps, and Kelly Bruton.Researchers with McMaster University and Denmark-based pharmaceutical company ALK-Abello A/S have made a groundbreaking discovery: a new...
Faulty DNA disposal system found to cause inflammation
by Salk Institute Endosomes (magenta) collect around mitochondria (blue) after infection with virus HSV-1, which attacks mtDNA (green) and causes its release. Credit: Salk InstituteCells in the human body contain power-generating mitochondria, each with their own mtDNA—a unique set of genetic instructions entirely separate from the cell’s nuclear DNA that mitochondria use to create life-giving energy....
Researchers identify potential way to treat genetic epilepsy by replacing ‘lost’ enzyme
by The Francis Crick Institute Credit: Pixabay/CC0 Public DomainScientists at the Francis Crick Institute have found a new treatment target for CDKL5 deficiency disorder (CDD), one of the most common types of genetic epilepsy. CDD causes seizures and impaired development in children, and medications are limited to managing symptoms rather than tackling the root cause of...
In a clinical trial, blood thinners added to clot-busting medication did not improve stroke outcomes
by American Heart Association Credit: CC0 Public DomainGiving blood thinners in addition to clot-busting medications to people with ischemic strokes (clot-caused strokes) did not improve their outcomes 90 days later, according to preliminary late-breaking science presented today at the American Stroke Association’s International Stroke Conference 2024. These results are from the MOST (Multi-Arm Optimization of Stroke...
Lipid mediator Maresin 1 helps improve muscle regeneration, finds study
by Michele Santillan, University of Michigan College of Engineering Skeletal muscle fibers. Credit: Berkshire Community College Bioscience Image Library / Public domainA team of researchers led by Carlos Aguilar, an associate professor of biomedical engineering at the University of Michigan, and graduate students Jesus Castor-Macias and Jacqueline Larouche, has sought to address how lipid mediators, which...
Bacteria in the mouth linked to pulmonary fibrosis survival
by University of Michigan Credit: CC0 Public DomainBacteria in the mouth may play a role in survival from idiopathic pulmonary fibrosis (IPF), finds a new study led by researchers from the University of Michigan and the University of Virginia. The findings come from a larger analysis of the role of the lung microbiome and IPF. Working...
Scientists code ChatGPT to design new medicine
by Chapman University Graphical abstract. Credit: Pharmaceuticals (2024). DOI: 10.3390/ph17020161Generative artificial intelligence platforms, from ChatGPT to Midjourney, grabbed headlines in 2023. But GenAI can do more than create collaged images and help write emails—it can also design new drugs to treat disease. Today, scientists use advanced technology to design new synthetic drug compounds with the right...
Cracking the code to vitamin D: How you store and cook your eggs mattersby Newcastle University
Credit: Unsplash/CC0 Public DomainScientists have shown that storing your eggs on the worktop rather than in the fridge—and how you cook them—matters when it comes to preserving vitamin D, known as the “sunshine vitamin.” Researchers at Newcastle University analyzed vitamin D-enriched eggs from the popular brand Happy Egg Co. to determine how the concentration of...