by EULAR Overview of the ACR/EULAR classification criteria for CPPD disease across the 4 Phases. Credit: Annals of the Rheumatic Diseases (2023). DOI: 10.1136/ard-2023-224575Calcium pyrophosphate deposition (CPPD) disease is a common, symptomatic arthritis, but until now there have been there are no validated classification criteria. This has hampered research in this common disease that becomes...
Peer-Reviewed Publication MEMORIAL SLOAN KETTERING CANCER CENTER AN IMMUNOFLUORESCENCE IMAGE OF AN AGED MOUSE LIVER. EXPRESSION OF Β-GALACTOSIDASE (WHITE) AND UPAR (YELLOW) IN SENESCENT CELLS SERVE AS TARGET FOR ENGINEERED CAR T CELLS. ELIMINATION OF THESE CELLS IMPROVED AGE-RELATED METABOLIC DYSFUNCTION. CREDIT: MEMORIAL SLOAN KETTERING CANCER CENTER HighlightsLaboratory research led by MSK and Cold Spring...
First study tracking how NK cells respond to the tumour microenvironment in real time discovered that stimulating the IL-15 pathway prevented the rapid loss of function and improved tumor controlPeer-Reviewed Publication UNIVERSITY OF BIRMINGHAM Some immune cells in our bodies see their ‘killer instinct’ restricted after entering solid tumours, according to new research. In a...
POSTED BY BOSTON UNIVERSITY It’s a grim projection: in 2024, for the first time ever, the United States is expected to surpass more than two million new cases of cancer in a year. The bleak forecast comes from the American Cancer Society’s latest annual cancer statistics report, released earlier this month. According to the society,...
A new wave of research is unpicking the relationship between cancer and neurons — and looking for ways to stop the crosstalk. McKenzie Prillaman A 3D model system shows how nerve cells (magenta) interact with cancer cells (green).Credit: Jennifer Su, Peter Wang, Nicole Lester, William L. Hwang Lightning bolts of lime green flashed chaotically across...
by Florey Institute of Neuroscience and Mental Health Credit: Florey Institute of Neuroscience and Mental HealthThe Florey’s Professor Anthony Hannan, Head of the Epigenetics and Neural Plasticity Group, and Research Co-Lead for the Mental Health Mission, said the results of a study published in Brain Behavior and Immunity indicate that dietary fiber could delay the...
by University of Auckland Credit: Pixabay/CC0 Public DomainA group of patients with a hereditary disorder have had their lives transformed by a single treatment of a breakthrough gene-editing therapy, according to the lead researcher of a trial published in the New England Journal of Medicine. The patients from New Zealand, the Netherlands and the UK have...
Akshay B. Jain, MD It’s that time of the year, when social media is rife with many top 5 and top 10 lists. Perhaps the beginning of a new year is a good time to review how different medications can have side effects beyond the disease state they’re used to address. Among the most common...
Peer-Reviewed Publication MEMORIAL SLOAN KETTERING CANCER CENTER MEMORIAL SLOAN KETTERING CANCER CENTER MEDICAL ONCOLOGIST EILEEN O’REILLY HELPED LEAD A CLINICAL TRIAL INVESTIGATING A READY-MADE VACCINE AS A TREATMENT FOR PANCREATIC AND COLORECTAL CANCERS WITH CERTAIN KRAS MUTATIONS.CREDIT: MEMORIAL SLOAN KETTERING A new vaccine shows encouraging early results as a potential off-the-shelf treatment for certain patients...
Selena Simmons-Duffin As an evolutionary anatomist, Heather Smith studies the fossil record of extinct species. Heather SmithIt was the first day of spring break in 1992 in Phoenix, Ariz. and 12-year-old Heather Smith was excited for her family’s upcoming ski trip But before Smith and her family had even packed their snow pants, she realized...
