by Emily LeClerc, University of Wisconsin-Madison Survival and differentiation of hPSC-derived neurons in fibrin hydrogel. Credit: Cell Stem Cell (2024). DOI: 10.1016/j.stem.2023.12.009A team of University of Wisconsin–Madison scientists has developed the first 3D-printed brain tissue that can grow and function like typical brain tissue. It’s an achievement with important implications for scientists studying the brain and...
by Tokyo University of Science Gut bacteria break down dietary fiber into short-chain fatty acids, which are known to affect our immune system. In this study, researchers investigated in detail the mechanisms by which these compounds mediate the activation of mast cells. Credit: Chiharu Nishiyama from Tokyo University of Science, JapanThe intricate relationship that exists between...
by American Heart Association Credit: Pixabay/CC0 Public DomainHaving a stroke may significantly increase the risk of developing dementia. The risk of dementia was the highest in the first year after a stroke and remained elevated over a period of 20 years, according to preliminary research presented at the American Stroke Association’s International Stroke Conference 2024, held...
by Nathi Magubane, University of Pennsylvania Confocal imaging demonstrating the dense network of capillary blood vessels in the lung that allow oxygen to move into our bloodstream. This complex vascular network can be severely disrupted upon viral infections like influenza and COVID-19, which greatly contributes to disease severity and mortality. Credit: Gan ZhaoIn the human body,...
by Dennis Thompson Certain copycat eyedrops may be contaminated and could give users an antibiotic-resistant eye infection, the U.S. Food and Drug Administration warned Wednesday. The packaging for South Moon, Rebright and FivFivGo eyedrops mirrors the packaging for Bausch & Lomb’s Lumify eyedrops, an over-the-counter product approved for red eye relief. However, samples of the...
by University of Würzburg The TUS technique has the potential to safely target deeper areas of the brain even at low energies. The elliptical blue area shows its area of influence in the current study, the right prefrontal cortex. This area is associated with brain regions that produce the EEG parameter of the mid-frontal theta frequency,...
by Translational Genomics Research Institute Credit: Pixabay/CC0 Public DomainIn a study published in the journal, Cells, a team of scientists describe using machine learning models to identify changes in RNA molecules of plasma extracellular vesicles (EVs) that may hold potential for identifying Alzheimer’s disease (AD) at its earliest stages. EVs are tiny particles released by the...
by Buck Institute for Research on Aging The art depicts the recovery of the functional plasticity at synapses on neurons despite tau-induced toxicity in the brain. Credit: Larissa BrownWhile newly approved drugs for Alzheimer’s show some promise for slowing the memory-robbing disease, the current treatments fall far short of being effective at regaining memory. What...
by Elodie Smith, Cornell University Tracking recruitment of hair follicle McSCs to the epidermis by UVB on unpigmented mouse dorsal skin. Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-45034-3Patients with an appearance-altering skin condition may have relief thanks to an unlikely cocktail of a molecule that induces labor, an immunosuppressant medication and controlled UVB irradiation. This College of...
by Rush University Medical Center Neutralization of p402 and p40 increases levels of IFN-γ in pancreatic cancer cells. Immunohistochemical analysis at 60× magnification of PANC-1 (A) and BxPC-3 cells (B) treated with p40 homodimer or p40 monomer were labeled with IFN-γ (red). DAPI was used to stain the nuclei. Cells positive for IFN-γ were counted and...
