by Keck School of Medicine of USC Credit: AI-generated imageIn one of the largest ever gene-environment interaction studies of red meat and colorectal cancer, which explored the impact of red meat consumption on a person’s cancer risk based on their genotype, researchers have identified two genetic markers that may help explain the association between the...
What Are the Most Gut-Healthy Foods?
Written by Nicole Andonian, MD | Reviewed by Katie E. Golden, MD Key takeaways: You have more bacteria in your gut than you do cells in your entire body. So it is important to keep them healthy for your overall health.Probiotic foods provide your gut with live, healthy bacteria. They can be found in dairy...
In Conversation: What do we know about the weight loss plateau on Wegovy?
Semaglutide drugs, used to treat type 2 diabetes, also help with weight management. One such drug, sold under the brand name Wegovy, is approved as a treatment for overweight and obesity. But why do some people hit a weight loss plateau on Wegovy? We explore this topic with our expert guest In Conversation. Illustration by...
Five Keys to Helping Long-COVID Patients Recover
About 7% of US adults report having or having had symptoms of long COVID such as fatigue, heart palpitations and/or dizziness. These are three of the 12 symptoms identified as part of the National Institute of Health’s RECOVER initiative that can be reliably used to classify someone as having long COVID. While there is no...
Focal Therapy for Prostate Cancer: Evidence-Based or Oversold?
Howard Wolinsky In 2013, a prostate-specific antigen (PSA) blood test revealed that Richard LaFrate’s levels had jumped. Previously in a normal range, LaFrate’s PSA was now above 6 ng/mL, indicating an elevated likelihood for prostate cancer. The jazz guitarist from Leesburg, Florida, then 70 years old, underwent a biopsy, which found two Gleason 6 lesions....
New Guidelines: Start PSA Screening Earlier in Black Men
Lowering the recommended age for baseline prostate-specific antigen (PSA) would reduce prostate cancer deaths by about 30% in Black men without significantly increasing the rate of overdiagnosis, according to new screening guidelines from the Prostate Cancer Foundation. Specifically, baseline PSA testing in Black men should begin at age 40-45, sooner than current guidelines recommend, and...
Smoking Cessation Before Age 40 Years Brings Great Benefits
Philippe Tellier, MD Chronic smoking remains a major cause of premature mortality on a global scale. Despite intensified efforts to combat this scourge, a quarter of deaths among middle-aged adults in Europe and North America are attributed to it. However, over the past decades, antismoking campaigns have borne fruit, and many smokers have quit before...
Is a 1-Hour Glucose Test Better at Predicting T2D Risk?
Miriam E. Tucker A new position statement from the International Diabetes Federation advises using a 1-hour 75-g oral glucose tolerance test (OGTT) to improve identification of people at risk of developing type 2 diabetes. “There are many, many people who may appear ‘normal’ if you use A1c or fasting glucose, but if you do a...
GLP-1s Don’t Appear to Worsen Diabetic Retinopathy
Richard Mark Kirkner SAN FRANCISCO ― A large observational registry study of almost 100,000 eyes has found that the diabetes drug semaglutide, a GLP-1 agonist recently approved for weight loss, does not worsen the progression of potentially vision-threatening diabetic retinopathy in the long term in patients taking the drug. However, the researchers said, the findings...
SGLT2 Inhibitors Protective Against Retinopathy in T2D
TOPLINE:Sodium-glucose cotransporter 2 (SGLT2) inhibitors are associated with a lower risk for sight-threatening retinopathy than other second-line glucose-lowering medications in patients with type 2 diabetes (T2D). METHODOLOGY:Researchers conducted a nationwide cohort study including 3,544,383 patients with newly diagnosed T2D.During the 5-year study period, 159,965 patients were treated with SGLT2 inhibitors, 304,383 received dipeptidyl peptidase-4 (DPP-4)...