July 26, 2024 by H. Lee Moffitt Cancer Center & Research Institute Credit: Pixabay/CC0 Public DomainMerkel cell carcinoma is a rare but highly aggressive form of skin cancer known for its rapid growth and tendency to metastasize. Despite the promise of immune checkpoint blockade therapy, which can boost the body’s immune response against cancer cells,...
July 26, 2024 by Tokyo Medical and Dental University The OS and GEFS of the study cohort. The solid line and the dashed line show OS and GEFS curves, respectively. OS and GEFS at 2 years post-HCT are described with 95% confidence intervals in brackets. Grade III–IV acute GVHD, systemically treated chronic GVHD, second transplantation,...
July 26, 2024 by Sichuan International Medical Exchange and Promotion Association Cordyceps sinensis (CS) improved mitochondrial dysfunction in bleomycin-induced BEAS-2B cells. (A) Representative transmission electron microscopy (TEM) images of BEAS-2B cells in the control, model, and CS groups. Credit: MedComm – Future Medicine (2024). DOI: 10.1002/mef2.91A study from China has reported that Cordyceps sinensis (CS),...
by Amanda Morris, Northwestern University Cartilage cells generate more protein components (collagen II and aggrecan) for regeneration when treated with fast-moving dancing molecules (left) compared to slower moving molecules. Credit: Stupp Research Group/Northwestern UniversityIn November 2021, Northwestern University researchers introduced an injectable new therapy, which harnessed fast-moving “dancing molecules,” to repair tissues and reverse paralysis...
July 26, 2024 by Medical Research Council (MRC) Laboratory of Medical Sciences X-linked human genetic variation associated with skewed X chromosome usage in blood-derived polyclonal B lymphoblastoid cells. Credit: Nature Genetics (2024). DOI: 10.1038/s41588-024-01840-5A study published in Nature Genetics by the Lymphoid Development Group at the MRC Laboratory of Medical Sciences reveals that the contribution...
July 26, 2024 by Tulane University Phosphorylation activation of CSF1R is increased with simian immunodeficiency virus. Credit: Brain (2024). DOI: 10.1093/brain/awae153An experimental drug originally developed to treat cancer may help clear HIV from infected cells in the brain, according to a new Tulane University study. For the first time, researchers at Tulane National Primate Research...
July 25, 2024 by Royal Australasian College of Surgeons Credit: Pixabay/CC0 Public DomainExpensive MRI exams are commonly used to evaluate patients with suspected gallstones, often delaying definitive intervention and increasing the risk of disease severity, further complications and longer hospital stays. Over a five-year period, five machine learning models were developed and tested to retrospectively...
July 25, 2024 by Julia Milzer, CU Anschutz Medical Campus HFHC-feeding recapitulates MASH phenotype in murine models. Credit: Hepatology (2024). DOI: 10.1097/HEP.0000000000000971A new study brings researchers closer to better understanding the pathology of the fatty liver disease MASH, which stands for metabolic dysfunction-associated steatohepatitis. MASH is a consequence of poor diet and obesity and results...
July 25, 2024 by University of Oxford Credit: CC0 Public DomainA study of more than 200,000 people by researchers at the University of Oxford found at least a 17% reduction in dementia diagnoses in the six years after the new recombinant shingles vaccination, equating to 164 or more additional days lived without dementia. The paper...
July 25, 2024 by The University of Hong Kong Global price of biosimilar infliximab in July 2022. Credit: JAMA Network Open (2024). DOI: 10.1001/jamanetworkopen.2024.18800A research team from the LKS Faculty of Medicine of the University of Hong Kong (HKUMed) performed a cost-effectiveness analysis of treatment strategies for patients in Hong Kong with rheumatoid arthritis. The...
