A new research paper published in Nature Communications lays the groundwork for the development of new drugs specific to genetic mutations or alterations responsible for the onset of tumours or genetic diseases Peer-Reviewed PublicationISTITUTO ITALIANO DI TECNOLOGIA – IIT IMAGE: BLOCKING OF THE SPLICING ACTIVE SITE BY SPECIFIC SMALL MOLECULES view moreCREDIT: ISABEL ROMERO CALVO/EMBL...
Month: <span>July 2024</span>
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Dual inhibition of cAMP responsive element binding protein 3 on AKT signaling supresses the progression of hepatocellular carcinoma
NEWS RELEASE 2-JUL-2024 Peer-Reviewed PublicationSICHUAN INTERNATIONAL MEDICAL EXCHANGE AND PROMOTION ASSOCIATION This study is led by Prof. Bixiang Zhang, Dr. Zhao Huang, Prof. Zeyang Ding, Dr. Huifang Liang (Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology). The experimental part was mainly conducted by Dr. Yi He, Dr. Shenqi Han,...
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HOW MELANOMA BECOMES RESISTANT TO TREATMENT
JULY 1ST, 2024 POSTED BY U. ZURICH UNIVERSITY UNIVERSITY OF ZURICHResearchers have discovered the mechanism behind melanoma’s resistance to treatment. These findings could pave the way for more effective therapies. Malignant melanoma is one of the most aggressive types of cancer. Despite recent progress in effective therapies, the tumors of many patients are either resistant...
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No organ is an island: Genetic study shows unique but interconnected aging markers
By Dr. Chinta Sidharthan Reviewed by Susha Cheriyedath, M.Sc. Jul 2 2024 In a recent study published in the journal Nature Aging, a team of researchers used a large dataset consisting of participants of European ancestry from the United Kingdom (U.K.) Biobank to explore the genetic underpinnings of the biological age gap or BAG, a...
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Brain study reveals cause of apathy in schizophrenia
University of Geneva Jul 2 2024 Schizophrenia, which affects up to 1% of the population, is a neuropsychiatric disorder characterized by multiple symptoms. One of the most common, and for which there is no treatment, is apathy and lack of motivation. By comparing neural activation between a group of patients and a control group during...
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Fermentable fibre may help to relieve long-COVID symptoms neuroscience
Research dietitian Jane Varney at Monash University in Melbourne, Australia, and co-workers will use their Global Grant for Gut Health to examine whether adding fermentable fibre to food could help reduce the symptoms and impact of long COVID. Metabolites produced by microbes in the gut (pictured) feeding on fermentable fibre may influence long COVID.Credit: THOM...
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Serendipity reveals new method to fight cancer with T cells
JULY 2, 2024 by Laura Red Eagle, University of Wisconsin-Madison Graphical abstract. Credit: Molecular Therapy – Methods & Clinical Development (2024). DOI: 10.1016/j.omtm.2024.101249A promising therapy that treats blood cancers by harnessing the power of the immune system to target and destroy cancer cells could now treat solid tumors more efficiently. Thanks to a recent study...
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The path to Parkinson’s disease: All roads lead to the nigrosome
JULY 2, 2024 by Tiziano Balzano , Medical Xpress The nigrosome has an intricate and dense network of highways and streets, representing its rich vascularization. This dense network makes the nigrosome a major intersection, a key entry point for traffic, including not only necessary supplies but also potentially harmful elements. Credit: Image created by OpenArt...
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Engineered plasma cells show long-lasting antileukemic activity in mice
JULY 2, 2024 by Cell Press Acute myelocytic leukemia (AML). Credit: Unsplash/CC0 Public Domain Researchers show for the first time that engineered human plasma B cells can be used to treat a disease—specifically leukemia—in a humanized animal model. The results mark a key step in the realization of ePCs as therapies to treat cancer, auto-immune...
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Genetic study points to oxytocin as possible treatment for obesity and postnatal depression
JULY 2, 2024 by University of Cambridge Credit: Unsplash/CC0 Public DomainScientists have identified a gene which, when missing or impaired, can cause obesity, behavioral problems and, in mothers, postnatal depression. The discovery, reported in Cell, may have wider implications for the treatment of postnatal depression, with a study in mice suggesting that oxytocin may alleviate...