August 3, 2024 by Elana Gotkine Semaglutide products are being sold online, with products likely unregistered or unlicensed, according to a research letter published online Aug. 2 in JAMA Network Open. Amir Reza Ashraf, Pharm.D., from the University of Pécs in Hungary, and colleagues conducted a risk assessment of semaglutide online sourcing. Websites advertising semaglutide...
Clinical trial shows JAK inhibitor improves multiple autoimmune conditions in patients with Down syndrome
August 13, 2024 by CU Anschutz Medical Campus Acutal results of clinical trial participant with alopecia areata after four months of treament. Credit: Linda Crnic Institute for Down Syndrome Multi-organ autoimmunity and widespread autoantibody production in Down syndrome.A new study published in eLife by researchers from the Linda Crnic Institute for Down Syndrome (Crnic Institute)...
Non-pharmacological interventions may play greater role in treatment of patients with Parkinson’s disease
August 13, 2024 by IOS Press Credit: Pixabay/CC0 Public DomainThe field of non-pharmacological interventions for the treatment of individuals with Parkinson’s disease (PD) is reaching maturity and has the potential to substantially improve patient care in the future. A supplement to the Journal of Parkinson’s Disease (JPD) captures a wealth of information on non-pharmacological interventions...
New research explores the urea cycle’s strong connection to fatty liver disease
August 13, 2024 by Indiana University School of Medicine New research explores the urea cycle’s strong connection to fatty liver diseaseCredit: Cell Metabolism (2024). DOI: 10.1016/j.cmet.2024.07.007An Indiana University School of Medicine physician scientist is making strides in understanding the molecular origins of fatty liver disease, a leading cause of liver failure in the United States....
Childhood maltreatment is associated with greater cognitive difficulties than previously thought
August 13, 2024 by King’s College London Credit: Unsplash/CC0 Public DomainNew research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College London and City University of New York suggests that the cognitive difficulties associated with childhood maltreatment, and particularly neglect, have been grossly underestimated in previous studies. The research, published in Lancet...
Massive biomolecular shifts occur in our 40s and 60s, researchers find
August 14, 2024 by Stanford University Medical Center Credit: Pixabay/CC0 Public DomainIf it’s ever felt like everything in your body is breaking down at once, that might not be your imagination. A new Stanford Medicine study shows that many of our molecules and microorganisms dramatically rise or fall in number during our 40s and 60s....
Researchers report potential new treatment regimens for multidrug-resistant TB meningitis
August 14, 2024 by Johns Hopkins University Researchers report potential new treatment regimens for multidrug-resistant TB meningitis18F-Pretomanid exposure in brain and lung tissues of a patient with active tuberculosis. Credit: Sanjay Jain LabIn a preliminary study with a small number of humans, rabbits and mice, researchers at Johns Hopkins Children’s Center say they have developed...
A new class of beige fat cells that burn energy via ‘futile cycles’ could lead to better metabolic health
August 14, 2024 by Fabio Bergamin, ETH Zurich Credit: Cell Metabolism (2024). DOI: 10.1016/j.cmet.2024.07.005Fat cells come in three colors: white, brown, and beige. White fat cells store fat in our body as an energy reserve. We need these cells, but having too many creates health problems. Brown fat cells are particularly active in infants. They...
Researchers discover an entirely new way to treat anxiety
Neuropsych — August 12, 2024 Researchers discover an entirely new way to treat anxietyManipulating a signaling pathway in mice reversed their anxiety — and offers hope for a new class of anti-anxiety medications for humans. Key TakeawaysRoughly a third of all Americans will experience an anxiety disorder at some point in their lives. While leading...
A new type of degenerative brain disease underlying dementia is very common among the oldest old
News Release 13-Aug-2024 A study at the University of Helsinki found brain changes associated with a novel degenerative brain disease causing dementia as common as one in every two individuals over the age of 85. Peer-Reviewed PublicationUniversity of Helsinki A new type of degenerative brain disease, limbic-predominant age-related TDP-43 encephalopathy (LATE), was recognised just a...