By Dr. Priyom Bose, Ph.D.Reviewed by Danielle Ellis, B.Sc. Proto-oncogenes are a group of genes that normally regulate cell division and growth by encoding regulator proteins for cell cycle, growth factors, transcription factors, DNA-binding proteins, and protein kinases that are involved in signal transduction. Upon mutation, proto-oncogenes change to oncogenes and transform normal cells into...
A transparent AI approach recalibrated the new PREVENT equations to provide a more tailored cardiovascular risk assessment in a local population Image credit: Clker-Free-Vector-Images from Pixabay Risk calculators are used to evaluate disease risk for millions of patients, making their accuracy crucial. But when national models are adapted for local populations, they often deteriorate, losing...
News Release 19-Sep-2024 Peer-Reviewed PublicationPohang University of Science & Technology (POSTECH) image: Image of wrinkled epithelium on the ECM hydrogel layer in response to compression Credit: POSTECH A research team consisting of Professor Dong Sung Kim, Professor Anna Lee, and Dr. Jaeseung Youn from the Department of Mechanical Engineering at POSTECH has successfully recreated the...
News Release 19-Sep-2024 A potential future target to cure severe anemia in patients unresponsive to standard treatments Peer-Reviewed PublicationKumamoto University image: When acute anemia occurs, very low-density lipoproteins (VLDL), which are involved in lipid transport, are broken down, releasing apolipoprotein E (ApoE). ApoE binds to its receptor (VLDLR) present on the cell membranes of certain...
News Release 19-Sep-2024 Peer-Reviewed PublicationThe Hebrew University of Jerusalem A new study reveals that reprogramming specialized cells to become different types of cells, a key process in regenerative medicine, faces a major hurdle. The challenge lies in the DNA methylation patterns of the cells, which are like cellular “memory” markers. This study reveals that these...
News Release 19-Sep-2024 The study, published in Cell, reveals an essential function of sodium transport in cellular energy generation Peer-Reviewed PublicationCentro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.) image: Jesús Vázquez Cobos, Iván López-Montero, Enrique Calvo Alcocer, Pablo Hernansanz Agustín, Carmen Morales Vidal, José Antonio Enríquez, Rebeca Acín Pérez, Sara Jaroszewicz and José Luis Cabrera...
September 18, 2024 by Fujita Health University In a new study, scientists investigated the impact of low sodium concentrations and its rapid correction on nitric oxide production dependent on expression of Nfat5 in microglial cells. Credit: Yoshihisa Sugimura from Fujita Health UniversityLow serum sodium concentrations in the blood are called hyponatremia, a prevalent clinical electrolyte...
September 18, 2024 by Cardiff University Graphical abstract. Credit: Journal of Clinical Investigation (2024). DOI: 10.1172/JCI164535For the first time, scientists have found that proteins from bacteria can trigger the immune system to attack insulin-producing cells, leading to the development of type 1 diabetes. The new research showed that killer T-cells—a type of white blood cell...
September 18, 2024 by Cleveland Clinic Credit: CC0 Public DomainA clinical trial has demonstrated that the cancer drug pomalidomide is safe and effective in treating hereditary hemorrhagic telangiectasia (HHT), a rare bleeding disorder that impacts more than one in 5,000 people worldwide. The trial, led by Keith McCrae, M.D., of Cleveland Clinic, was stopped early...
September 19, 2024 by Benedicte REY Zoom out: Video calls have become part of daily life for many — particularly since the pandemic.Feel drained after a long video call? Your tiredness could be partly linked to the background on your screen, according to a study published on Thursday which suggested trying an image depicting nature....
